Scientific American Content: Global
Men Resist Green Behavior as Un-Manly Women have long surpassed men in the arena of environmental action; across age groups and countries, females tend to live a more eco-friendly lifestyle. Compared to men, women litter less , recycle more , and leave a smaller carbon footprint . Some researchers have suggested that personality differences, such as women’s prioritization of altruism, may help to explain this gender gap in green beha
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EurekAlert! - Breaking News
Researchers describe first-ever hybrid bird species from the Amazon IMAGE: The male golden-crowned manakin has evolved yellow feathers, likely as a way to attract potential female mates. view more Credit: University of Toronto Scarborough A team of U of T Scarborough researchers have described the first known hybrid bird species to be found in the Amazon rainforest. Through a series of genetic and other tests the team have revealed that the golden-crowned m
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Ingeniøren
Danmarks nye referencegenom er årets vigtigste forskningsresulatat VIDENSKABENS TOP-5 – VINDER Et referencegenom er af afgørende betydning for at kunne diagnosticere og behandle genetiske sygdomme. At lave et sådant helt fra bunden uden simplificerende antagelser er en kompliceret opgave, der kræver mange forskere, kompliceret udstyr og stor computerkraft. Med støtte fra Danmarks Innovationsfond og andre kilder har forskere fra DTU, Københavns Universitet og Aar
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Three Pots, Three Mashes | Moonshiners #Moonshiners | Tuesdays 9p Mark and Digger assemble their 3 pot still system after getting off to a late start. A month behind schedule, can their vanilla bean moonshine save the season? Full Episodes Streaming FREE: https://discovery.com/tv-shows/moonshiners/ Subscribe to Discovery: http://bit.ly/SubscribeDiscovery Join us on Facebook: https://www.facebook.com/Discovery https://www.facebook.com/
14min
Latest Science News -- ScienceDaily
Hackers could guess your phone PIN using its sensor dataInstruments in smart phones such as the accelerometer, gyroscope and proximity sensors represent a potential security vulnerability, according to researchers.
33min
Latest Science News -- ScienceDaily
Understanding the molecular mechanisms of ALSScientists have revealed more details of the molecular mechanism behind neuronal cell death in amyotrophic lateral sclerosis (ALS), a step forward to find ways to control progression of the disease.
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Latest Science News -- ScienceDaily
Pulmonary fibrosis caused by single transcription factorTo date, the molecular basis of pulmonary fibrosis has been poorly understood. Scientists have now shown that reduced activity of the transcription factor FoxO3 plays a key role in the development of the disease. In research on mice, the progress of the disease was able to be halted using drugs that boost FoxO3 activity. The researchers are hoping they may have found a possible approach to treatme
33min
Big Think
Analysis of Giant Hats Reveals the Secrets of the People of Easter Island Easter Island is one of the most mysterious places on Earth, largely due to the strange art left behind by its ancient inhabitants. This remote Chilean island in southeastern Pacific Ocean is home to 887 monumental stone statues or Moai , created by the Polynesian Rapa Nui people who used to live there. The questions about the statues have always abounded - why do they all look like giant hea
41min
Popular Science
The accessories you need to keep holiday gadget gifts working like new After ferociously tearing wrapping paper, mangling bows, and littering the floor with a rainbow of tissue, the merry season of gift giving is officially over. But while our arms and closets are now freshly filled with shiny high-tech presents, that booty leaves us with something new to think about: How do we keep all those toys in good shape and proper working order for as long as possible? Here'
44min
Latest Science News -- ScienceDaily
New hope for stopping an understudied heart disease in its tracksThanks, in part, to pigs, scientists now are catching up on understanding the roots of calcific aortic valve disease (CAVD).
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Latest Science News -- ScienceDaily
Cleaner air, longer livesA new study shows that the Clean Air Act is likely responsible for dramatic decline in atmospheric organic aerosol in the U.S.
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Latest Science News -- ScienceDaily
Potential path to repair MS-damaged nervesGene expression in specific cells and in specific regions can provide a more precise, neuroprotective approach than traditional treatments for neurological diseases. For multiple sclerosis, specifically, increasing cholesterol synthesis gene expression in astrocytes of the spinal cord can be a pathway to repair nerves that affect walking.
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Latest Science News -- ScienceDaily
First-ever hybrid bird species from the AmazonResearchers have described the first known hybrid bird species to be found in the Amazon rainforest. Through a series of genetic and other tests the team have revealed that the golden-crowned manakin -- first discovered in Brazil in 1957 but not seen again until 2002 - is in fact a hybrid species.
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EurekAlert! - Breaking News
Short-term exposure to low levels of air pollution linked with premature death among US seniors Boston, MA - Short-term exposures to fine particulate air pollution and ozone--even at levels well below current national safety standards--were linked to higher risk of premature death among the elderly in the U.S. according to a new study from Harvard T.H. Chan School of Public Health. The risk was even higher among elderly who were low-income, female, or Black. The study will be published
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EurekAlert! - Breaking News
Are childhood blood lead levels associated with criminal behavior? Bottom Line: Researchers found no consistent association between childhood lead exposure and adult criminal behavior in New Zealand where low socioeconomic status, which confuses the association in settings with socioeconomic disparities, is less of a factor. Why The Research Is Interesting: Lead has well-documented effects on the brain and there is no safe level of exposure. Some research sugges
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EurekAlert! - Breaking News
Calcium, vitamin D supplements not associated with lower risk of fractures Bottom Line: Supplements containing calcium, vitamin D or both did not appear to protect against hip fracture and other bone breaks in older adults. Why The Research Is Interesting: Practice guidelines recommend calcium and vitamin D supplements for older people to prevent fractures in those with osteoporosis; previous studies have come to mixed conclusions about an association between supplement
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EurekAlert! - Breaking News
Short-term exposure to air pollution at levels below current standards and risk of death Bottom Line: Short-term exposure to air pollution at levels below current air quality standards were associated with a higher risk of death in older adults. Why The Research Is Interesting: The Clean Air Act requires that National Ambient Air Quality Standards for fine particulate matter and ozone be reviewed every five years. Estimates of the risk of death at air pollution levels below the curre
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EurekAlert! - Breaking News
Brainstem changes underlie sound sensitivity in fragile X mouse model Developmental changes in the brainstem driven by fragile X syndrome (FXS) -- a condition that often co-occurs with autism spectrum disorder in humans -- may underlie the hypersensitivity to sound observed in both humans and a mouse model of the disorder, according to animal research published in eNeuro . Sarah Rotschafer and Karina Cramer studied groups of sound-processing neurons in the brainste
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EurekAlert! - Breaking News
Dietary restriction and life span in male and hermaphrodite worms IMAGE: This is a microscopy image of a hermaphrodite C. elegans . view more Credit: Nishida Lab An organism's lifespan is known to be affected by its sex and diet, but where these two factors overlap biologically is not well understood. Researchers in Japan looked for clues in worms-- C. elegans --that have two sexes: hermaphrodite or male. They found that hermaphrodite worms can live o
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EurekAlert! - Breaking News
Researchers find potential path to repair MS-damaged nerves FINDINGS Gene expression in specific cells and in specific regions can provide a more precise, neuroprotective approach than traditional treatments for neurological diseases. For multiple sclerosis, specifically, increasing cholesterol synthesis gene expression in astrocytes of the spinal cord can be a pathway to repair nerves that affect walking. BACKGROUND Multiple sclerosis is an autoimmune, n
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EurekAlert! - Breaking News
Blood pressure control best achieved with a multilevel, multicomponent approachCurrent clinical guidelines recommend lower blood pressure targets for the general population, yet control remains elusive for most. A new study suggests that patients with hypertension can best achieve blood pressure control with a multilevel, multicomponent approach that includes physician- and non-physician-led interventions. The findings from a comparative effectiveness review are published in
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Latest Science News -- ScienceDaily
Shape separates substanceResearchers report a new physical model that shows how the topology of a porous material influences the phase separation of binary mixtures. The model uses two variables, the density field of a porous structure and the composition field of a binary mixture, to show that topology has very different effects on phase separation depending on the porous structure being random and either 2D or 3D.
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Latest Science News -- ScienceDaily
Electronically-smooth '3-D graphene': A bright future for trisodium bismuthideResearchers have found that the topological material trisodium bismuthide (Na3Bi) can be manufactured to be as 'electronically smooth' as the highest-quality graphene-based alternative, while maintaining graphene's high electron mobility.
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Latest Science News -- ScienceDaily
Analysis of new studies including 250,000 people confirms sugar-sweetened drinks are linked to overweight and obesity in children and adultsA new review of the latest evidence on sugar-sweetened beverages (SSBs)- which includes 30 new studies published between 2013 and 2015 (and none of them industry sponsored) -- concludes that SSB consumption is associated with overweight and obesity, and that countries that have not already done so should take action to reduce the consumption of the so-called 'empty calories' that these drinks cont
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Latest Science News -- ScienceDaily
New loci associated with asthma enriched in epigenetic marksScientists have discovered five new regions of the genome that increase the risk of asthma.
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Science : NPR
After Harvey, Texans Are Preparing For Future With Raised Homes, Private Flood Gates Houston, the nation's fourth largest city, is planning to remake itself into a more flood-proof metropolis after Hurricane Harvey hit the region hard. But Texas still doesn't have the money it wants to do that, let alone detailed plans on how to spend it. Some Texans simply aren't waiting; they're forging ahead on their own.
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Science : NPR
As Corals Wither Around The World, Scientists Try IVF One organization is trying to save dying reefs by fertilizing coral in the lab, like this spawning colony of Acropora digitifera. Mike McCue/Courtesy of SECORE International hide caption toggle caption Mike McCue/Courtesy of SECORE International One organization is trying to save dying reefs by fertilizing coral in the lab, like this spawning colony of Acropora digitifera. Mike McCue/Courtesy of
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Latest Science News -- ScienceDaily
How small does your rice pudding need to get when stirring jam into it?Have you ever tried turning the spoon back after stirring jam into a rice pudding? It never brings the jam back into the spoon. This ever-increasing disorder is linked to the notion of entropy. In a new study, researchers demystify the clash between two theories of entropy by analyzing the practical consequences in two well-defined size systems, with a view to confirming them experimentally.
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Latest Science News -- ScienceDaily
Revised 'McDonald criteria' expected to speed the diagnosis of multiple sclerosisThe McDonald Criteria for the Diagnosis of Multiple Sclerosis have just been revised in hopes of speeding diagnosis and reducing the chance of misdiagnosis.
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Latest Science News -- ScienceDaily
Zika remains a research and public health challengeThe Zika virus has become established in more than 80 countries, infected millions of people, and left many babies with birth defects. Although scientists have made progress in their understanding of the virus, it would be premature to think that the Zika pandemic is now under control and will not reemerge, perhaps more aggressively, say experts.
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Latest Science News -- ScienceDaily
Breaking up (protein complexes) is hard to do, but new study shows howA new study has identified the structural basis for how tightly bound protein complexes are broken apart to become inactivated.
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Latest Science News -- ScienceDaily
Anti-inflammatory antibodies may treat autoimmune diseaseA team of investigators has found a way to engineer antibodies within an organism, converting autoantibodies that attack 'self' tissues into anti-inflammatory antibodies in animal models of two autoimmune diseases.
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EurekAlert! - Breaking News
2017 top science news release breaks EurekAlert!'s all-time record The most popular news release on EurekAlert! in 2017 is also the most-visited in the science-news service's 21-year history. Attracting 898,848 views since April, the University of Central Florida release -- describing an artificial photosynthesis process that cleans air while producing energy , complete with video -- outperformed a 2012 announcement of trending releases from that year, which h
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Popular Science
This is how a molten salt nuclear reactor works Radioactive elements produce heat as they decay. Nuclear plants draw power from this process, and typically ­stabilize the temperature with water. But during a power outage, H2O—which needs pumps to flow—can’t always prevent meltdowns. Molten salt reactors, which instead control heat with melted lithium and potassium fluorides, have a fail-safe: If the electricity dies, a plug will melt, causing
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Popular Science
The World Health Organization may soon recognize video game addiction Most of us understand how diseases like alcoholism and drug addiction can cause pain and suffering. Craving a cigarette or a stiff drink on occasion is one thing, but addiction forces an individual to behave in unusual—and often destructive—ways in the service of finding the next fix. But you can also become addicted to behaviors, like gambling. And medical professionals are starting to realize t
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Big Think
Taking Small Breaks Appears Helpful for Your Memory I walked by the Au Bon Pain at the Rutgers Student Center on many a late night, wondering who those students were hunkered down over their books while fueling up on endless draughts of caffeine. It was foreign to me, being a morning person; the notion of spending the midnight to dawn hours trying to remember information never seemed plausible. how-memory-works The all-night cram has since b
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Phys.org - latest science and technology news stories
Russia launches telecoms satellite for Angola Russia on Tuesday launched a rocket carrying Angosat-1, the first national telecoms satellite for Angola, from its Baikonur space pad, with rare use of a rocket from Ukraine despite collapsed ties between the two nations. Live footage aired by Roscosmos space corporation showed the spacecraft take off into the night from the freezing launch pad in Kazakhstan. It reached initial orbit shortly afte
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Phys.org - latest science and technology news stories
Scientists get early look at hurricane damage to Caribbean coral reefs Before and after views of a coral reef off the coast of St. John, US Virgin Islands. The reef, vibrant and full of life, is pictured in 2013 (left). The same reef is shown from a different view in 2017 (right), after hurricanes Maria and Irma tore through the region. The reef is now more sparsely populated, with many coral colonies either severely damaged or swept away. Credit: Howard Lasker When
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EurekAlert! - Breaking News
Neuroscientists shed light on causes of postpartum depression using new research model IMAGE: Tufts University neuroscientists Jamie Maguire (left) and Laverne Melón have generated a novel preclinical model of postpartum depression and demonstrated involvement of the neuroendocrine system that mediates physiological response to... view more Credit: Anna Derian for Tufts University BOSTON (Dec. 26, 2017)--Postpartum depression strikes nearly one in five new mothers, who may experien
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Popular Science
In all likelihood, someday the sun will knock out the grid S hortly after sunset on June 18, 2013, a woman drove her minivan onto Brighton Street in Belmont, Massachusetts. Her GPS told her to turn right. But the metallic voice, guided by satellite data, steered her wrong: onto a railroad track. She tried to drive off, but the van got stuck. No sooner had she ­unbuckled herself and her two kids and ushered them out than a train crumpled her car into a ba
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Inside Science
Safer Bricklaying with Artificial Intelligence Safer Bricklaying with Artificial Intelligence AI is helping to identify safer techniques in construction work. Bricklayer.jpg Image credits: The Royal Library, Denmark Technology Tuesday, December 26, 2017 - 14:30 Marcus Woo, Contributor (Inside Science) -- Bricklaying is repetitive and strenuous. It takes a toll on your body, potentially spraining, tearing and straining ligaments and muscles. B
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Live Science
Why Was Christmas So Cold This Year? It was a frigid Christmas in much of the United States. Chicago and Minneapolis both experienced their coldest December 25ths in decades. Erie, Pennsylvania weathered a stunning lake-effect storm that dumped more than 4 feet (1.2 meters) of snow on the city , shattering state records and prompting the local government to declare a snow emergency. And both Portland, Oregon and Seattle had a
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Phys.org - latest science and technology news stories
Feral hog poison field tests in Texas, Alabama in 2018 In this Aug. 24, 2011, file photo, a feral hog stands in a holding pen at Easton View Outfitters in Valley Falls, N.Y. New York has since eradicated feral swine within its boundaries, but such hogs still do more than $1.5 billion a year in damage around the country, and scientists are taking what could be a big step toward controlling them. They are field-testing poison baits made from a preserva
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Phys.org - latest science and technology news stories
Amid sales drop, Harley-Davidson wants to teach more to ride Harley-Davidson is placing a renewed emphasis on teaching people to ride as part of its efforts to attract more customers. The Milwaukee-based company 's decision to expand the number of dealerships with a Harley "Riding Academy" comes as the industry grapples with years of declining sales and an aging customer base. The program launched in 2000 with about 50 locations and now 245 dealerships i
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Phys.org - latest science and technology news stories
Self-fertilizing fish have surprising amount of genetic diversity Luana Lins and colleagues have sequenced the genome of the mangrove killifish, one of only two self-fertilizing vertebrates, and found it has a remarkable amount of genetic diversity for a fish that replicates mostly its own DNA. Credit: Washington State University As weird animals go, the mangrove killifish is in a class of its own. It flourishes in both freshwater and water with twice as much s
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The Atlantic
Photos of Midnight Mass and Holy Observances of Christmas After many images of Santa Claus, bright lights, and shopping malls, here is one last photo visit to Christmas focusing on the holy aspect—the commemoration of the birth of Jesus Christ and the varying Christian observances taking place around the world, often at midnight. Gathered here are Christmas services and observances from China, Kenya, Iran, Iraq, England, the U.S., India, Indonesia, Nige
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Latest Science News -- ScienceDaily
Alaskan microgrids offer energy resilience and independenceThe electrical grid in the contiguous United States is a behemoth of interconnected systems. If one section fails or is sabotaged, millions of citizens could be without power. Remote villages in Alaska provide an example of how safeguards could build resilience into a larger electrical grid. These communities rely on microgrids -- small, local power stations that operate autonomously.
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Big Think
Motivation Is a Bigger Advantage than Your IQ Score The IQ test has been the most widely used tool for assessing intelligence and giftedness as well as predicting school and job performance. But is it really the best and most accurate way to gauge future achievement? Psychologists and educators have been looking in other directions to identify the qualities that give the biggest advantage in life. The psychologist Howard Gardner was one of the fir
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Live Science
What Is 'Water Memory'? Why This Homeopathy Claim Doesn't Hold Water The U.S. Food and Drug Administration announced Dec. 18 that it plans to crack down on dangerous or dishonestly advertised homeopathic products — a class of products that sellers claim treat diseases by delivering extremely diluted traces of the substances that cause those diseases in the first place. If certain homeopathic remedies become more difficult to access due to the crackdown, what wil
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Proceedings of the National Academy of Sciences current issue
Acknowledgment of Reviewers, 2017 [Reviewer Acknowledgment] Acknowledgment of Reviewers, 2017 The PNAS editors would like to thank all the individuals who dedicated their considerable time and expertise to the journal by serving as reviewers in 2017. Their generous contribution is deeply appreciated. A Hillie Aaldering Lauri A. Aaltonen Duur K. Aanen Matthew L. Aardema Dirk G. A. L. Aarts Adam R. Abate Cory Abate-Shen Peter Abbamonte Abul K. Abbas Emmanue
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Proceedings of the National Academy of Sciences current issue
In This Issue [This Week in PNAS] In This Issue Water management system in ancient China Map of the Liangzhu city and hydraulic system, lower Yangtze River, China. The ancient Liangzhu culture of China represents a peak of early social and cultural development that preceded the Chinese dynasties of the historical record. The Liangzhu were an agrarian society and strongly influenced by rainfall patterns. Bin Liu et al. (pp. 13637–
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Proceedings of the National Academy of Sciences current issue
Intercellular competition and levels of development: The plasticity of inevitability [Biological Sciences] Intercellular competition and levels of development: The plasticity of inevitability Robert B. Eckhardt a , 1 , Alex S. Weller b , and Maciej Henneberg c a Laboratory for the Study of Morphology, Mechanics and Molecules, Department of Kinesiology, Pennsylvania State University , University Park, PA 16802; b Department of Medicine, Rutgers–New Jersey Medical School , Newark, NJ 07103; c Adelaide M
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Proceedings of the National Academy of Sciences current issue
NO and COX2: Dual targeting for aggressive cancers [Pharmacology] NO and COX2: Dual targeting for aggressive cancers A number of tumor-specific characteristics are known to associate with a cancer’s growth, metastatic potential, and response to therapy. Among these are mutational load and gene-expression patterns in the tumor cells and the interaction of the tumor cells with the many cellular and noncellular components that comprise the microenvironment of the
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Proceedings of the National Academy of Sciences current issue
Photochemistry of highly excited states [Chemistry] Photochemistry of highly excited states R. D. Levine a , b , c , 1 a The Fritz Haber Center for Molecular Dynamics and Institute of Chemistry, The Hebrew University of Jerusalem , Jerusalem 91904, Israel; b Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California, Los Angeles , CA 90095; c Department of Chemistry and Biochemistry, University of C
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Proceedings of the National Academy of Sciences current issue
Dopamine prediction error responses update demand [Neuroscience] Dopamine prediction error responses update demand According to the law of demand, the quantity demanded for a reward is dependent upon the price; as the price of the reward increases, the quantity demanded decreases ( 1 ). Conversely, when the price decreases, the quantity demanded increases. This relationship can be observed at any local bar during “happy hour,” a limited time during which the p
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Proceedings of the National Academy of Sciences current issue
The hydraulic lift of early states societies [Anthropology] The hydraulic lift of early states societies Vernon L. Scarborough a , 1 a Department of Anthropology, University of Cincinnati , Cincinnati, OH 45221-0380 The trajectory of social complexity is hardly a linear progression, with twists and turns precipitated by unintended consequences, consequences that can be advantageous or deleterious to a society and the biophysical environment that society i
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Proceedings of the National Academy of Sciences current issue
How reduced excitonic coupling enhances light harvesting in the main photosynthetic antennae of diatoms [Biophysics and Computational Biology] How reduced excitonic coupling enhances light harvesting in the main photosynthetic antennae of diatoms Tjaart P. J. Krüger a , 1 , Pavel Malý b , c , Maxime T. A. Alexandre b , Tomáš Mančal c , Claudia Büchel d , and Rienk van Grondelle a , b a Department of Physics, University of Pretoria , Hatfield 0028, South Africa; b Department of Physics and Astronomy, Vrije Universiteit Amsterdam , 1081 H
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Proceedings of the National Academy of Sciences current issue
Ultrafast 25-fs relaxation in highly excited states of methyl azide mediated by strong nonadiabatic coupling [Chemistry] Ultrafast 25-fs relaxation in highly excited states of methyl azide mediated by strong nonadiabatic coupling William K. Peters a , b , 1 , David E. Couch a , b , Benoit Mignolet c , Xuetao Shi d , Quynh L. Nguyen a , b , Ryan C. Fortenberry e , H. Bernhard Schlegel d , Françoise Remacle c , Henry C. Kapteyn a , b , Margaret M. Murnane a , b , 1 , and Wen Li d a JILA, University of Colorado , Boul
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Proceedings of the National Academy of Sciences current issue
Designing flexible 2D transition metal carbides with strain-controllable lithium storage [Chemistry] Designing flexible 2D transition metal carbides with strain-controllable lithium storage Hang Zhang a , b , Zhongheng Fu a , b , Ruifeng Zhang a , b , 1 , Qianfan Zhang a , b , Hongzhen Tian a , b , Dominik Legut c , Timothy C. Germann d , Yuanqi Guo a , b , Shiyu Du e , and Joseph S. Francisco f , g , 1 a School of Materials Science and Engineering, Beihang University , Beijing 100191, People’s
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Proceedings of the National Academy of Sciences current issue
Global biogeochemical cycle of vanadium [Earth, Atmospheric, and Planetary Sciences] Global biogeochemical cycle of vanadium William H. Schlesinger a , 1 , Emily M. Klein a , and Avner Vengosh a a Earth and Ocean Sciences, Nicholas School of the Environment, Duke University , Durham, NC 27708 Contributed by William H. Schlesinger, November 9, 2017 (sent for review September 1, 2017; reviewed by Robert A. Duce, Andrew J. Friedland, and James N. Galloway) Significance Human emissio
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Proceedings of the National Academy of Sciences current issue
Population is the main driver of war group size and conflict casualties [Anthropology] Population is the main driver of war group size and conflict casualties Rahul C. Oka a , 1 , Marc Kissel b , Mark Golitko a , Susan Guise Sheridan a , Nam C. Kim c , and Agustín Fuentes a a Department of Anthropology, University of Notre Dame , Notre Dame IN 46556; b Department of Anthropology, Appalachian State University , Boone, NC 28608; c Department of Anthropology, University of Wisconsin–M
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Proceedings of the National Academy of Sciences current issue
Molecular and functional resemblance of differentiated cells derived from isogenic human iPSCs and SCNT-derived ESCs [Applied Biological Sciences]Patient-specific pluripotent stem cells (PSCs) can be generated via nuclear reprogramming by transcription factors (i.e., induced pluripotent stem cells, iPSCs) or by somatic cell nuclear transfer (SCNT). However, abnormalities and preclinical application of differentiated cells generated by different reprogramming mechanisms have yet to be evaluated. Here we investigated the molecular...
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Proceedings of the National Academy of Sciences current issue
Comparative transcriptomics as a guide to natural product discovery and biosynthetic gene cluster functionality [Biochemistry] Comparative transcriptomics as a guide to natural product discovery and biosynthetic gene cluster functionality Gregory C. A. Amos a , Takayoshi Awakawa a , b , Robert N. Tuttle a , Anne-Catrin Letzel a , Min Cheol Kim a , Yuta Kudo a , William Fenical a , c , Bradley S. Moore a , c , d , and Paul R. Jensen a , c , 1 a Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceano
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Proceedings of the National Academy of Sciences current issue
Discovery of the leinamycin family of natural products by mining actinobacterial genomes [Biochemistry] Discovery of the leinamycin family of natural products by mining actinobacterial genomes Guohui Pan a , 1 , Zhengren Xu a , 1 , Zhikai Guo a , Hindra a , Ming Ma a , Dong Yang a , b , Hao Zhou a , Yannick Gansemans c , Xiangcheng Zhu d , e , Yong Huang d , Li-Xing Zhao f , Yi Jiang f , Jinhua Cheng g , h , Filip Van Nieuwerburgh c , Joo-Won Suh g , h , Yanwen Duan d , e , and Ben Shen a , b , i ,
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Proceedings of the National Academy of Sciences current issue
Rapid, direct activity assays for Smoothened reveal Hedgehog pathway regulation by membrane cholesterol and extracellular sodium [Biochemistry] Rapid, direct activity assays for Smoothened reveal Hedgehog pathway regulation by membrane cholesterol and extracellular sodium Benjamin R. Myers a , b , c , d , 1 , 2 , Lila Neahring a , b , c , d , 1 , 3 , Yunxiao Zhang a , b , c , d , Kelsey J. Roberts a , b , c , d , and Philip A. Beachy a , b , c , d , 2 a Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School
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Proceedings of the National Academy of Sciences current issue
Molecular mechanism for the subversion of the retromer coat by the Legionella effector RidL [Biophysics and Computational Biology] Molecular mechanism for the subversion of the retromer coat by the Legionella effector RidL Miguel Romano-Moreno a , Adriana L. Rojas a , Chad D. Williamson b , David C. Gershlick b , María Lucas a , Michail N. Isupov c , Juan S. Bonifacino b , Matthias P. Machner d , 1 , and Aitor Hierro a , e , 1 a Structural Biology Unit, Centro de Investigación Cooperativa en Biociencias , 48160 Derio, Spain;
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Proceedings of the National Academy of Sciences current issue
Cytoplasmic Cl- couples membrane remodeling to epithelial morphogenesis [Cell Biology] Cytoplasmic Cl − couples membrane remodeling to epithelial morphogenesis Mu He a , Wenlei Ye a , Won-Jing Wang d , Eirish S. Sison a , c , Yuh Nung Jan a , b , c , and Lily Yeh Jan a , b , c , 1 a Department of Physiology, University of California, San Francisco , CA 94158; b Department of Biochemistry and Biophysics, University of California, San Francisco , CA 94158; c Howard Hughes Medical Ins
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Proceedings of the National Academy of Sciences current issue
Daple coordinates organ-wide and cell-intrinsic polarity to pattern inner-ear hair bundles [Cell Biology] Daple coordinates organ-wide and cell-intrinsic polarity to pattern inner-ear hair bundles Kimberly Siletti a , b , Basile Tarchini c , 1 , 2 , and A. J. Hudspeth a , b , 1 , 2 a Howard Hughes Medical Institute , The Rockefeller University , New York, NY 10065; b Laboratory of Sensory Neuroscience, The Rockefeller University , New York, NY 10065; c The Jackson Laboratory , Bar Harbor, ME 04609 Co
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Proceedings of the National Academy of Sciences current issue
Regulatory networks specifying cortical interneurons from human embryonic stem cells reveal roles for CHD2 in interneuron development [Developmental Biology] Regulatory networks specifying cortical interneurons from human embryonic stem cells reveal roles for CHD2 in interneuron development Kesavan Meganathan a , Emily M. A. Lewis a , Paul Gontarz a , Shaopeng Liu a , Edouard G. Stanley b , Andrew G. Elefanty b , James E. Huettner c , Bo Zhang a , and Kristen L. Kroll a , 1 a Department of Developmental Biology, Washington University School of Medicin
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Proceedings of the National Academy of Sciences current issue
Troy/TNFRSF19 marks epithelial progenitor cells during mouse kidney development that continue to contribute to turnover in adult kidney [Developmental Biology] Troy/TNFRSF19 marks epithelial progenitor cells during mouse kidney development that continue to contribute to turnover in adult kidney Frans Schutgens a , b , Maarten B. Rookmaaker b , Francis Blokzijl c , d , Ruben van Boxtel c , d , Robert Vries e , Edwin Cuppen c , d , Marianne C. Verhaar b , and Hans Clevers a , 1 a Hubrecht Institute–Royal Netherlands Academy of Arts and Sciences , 3584 CT
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Proceedings of the National Academy of Sciences current issue
Zooplankton can actively adjust their motility to turbulent flow [Ecology] Zooplankton can actively adjust their motility to turbulent flow François-Gaël Michalec a , 1 , Itzhak Fouxon a , Sami Souissi b , and Markus Holzner a a Institute of Environmental Engineering, Swiss Federal Institute of Technology, 8093 Zurich, Switzerland; b Laboratoire d’Océanologie et de Géosciences, Université de Lille , CNRS, Université Littoral Côte d’Opale, UMR 8187, F 62930 Wimereux, Fra
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Proceedings of the National Academy of Sciences current issue
Ser7 of RNAPII-CTD facilitates heterochromatin formation by linking ncRNA to RNAi [Genetics] Ser7 of RNAPII-CTD facilitates heterochromatin formation by linking ncRNA to RNAi Takuya Kajitani a , b , 1 , Hiroaki Kato c , Yuji Chikashige d , Chihiro Tsutsumi d , Yasushi Hiraoka d , e , Hiroshi Kimura f , Yasuyuki Ohkawa g , Chikashi Obuse h , Damien Hermand i , and Yota Murakami a , 1 a Graduate School of Science, Hokkaido University , Sapporo, Hokkaido 060-0810, Japan; b Graduate School o
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Proceedings of the National Academy of Sciences current issue
Effects of mutation and selection on plasticity of a promoter activity in Saccharomyces cerevisiae [Genetics] Effects of mutation and selection on plasticity of a promoter activity in Saccharomyces cerevisiae Fabien Duveau a , 1 , David C. Yuan b , 1 , Brian P. H. Metzger a , Andrea Hodgins-Davis a , and Patricia J. Wittkopp a , b , 2 a Department of Ecology and Evolutionary Biology, University of Michigan , Ann Arbor, MI 48109; b Department of Molecular, Cellular, and Developmental Biology, University o
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Proceedings of the National Academy of Sciences current issue
ATG-dependent phagocytosis in dendritic cells drives myelin-specific CD4+ T cell pathogenicity during CNS inflammation [Immunology and Inflammation] ATG-dependent phagocytosis in dendritic cells drives myelin-specific CD4 + T cell pathogenicity during CNS inflammation Christian W. Keller a , Christina Sina a , b , Monika B. Kotur a , Giulia Ramelli a , Sarah Mundt c , Isaak Quast a , d , Laure-Anne Ligeon e , Patrick Weber a , Burkhard Becher c , Christian Münz e , and Jan D. Lünemann a , f , 1 a Institute of Experimental Immunology, Laborato
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Proceedings of the National Academy of Sciences current issue
Sclerostin influences body composition by regulating catabolic and anabolic metabolism in adipocytes [Medical Sciences] Sclerostin influences body composition by regulating catabolic and anabolic metabolism in adipocytes Soohyun P. Kim a , 1 , Julie L. Frey a , 1 , Zhu Li a , Priyanka Kushwaha a , Meredith L. Zoch a , Ryan E. Tomlinson a , Hao Da a , Susan Aja b , c , Hye Lim Noh d , Jason K. Kim d , e , f , Mehboob A. Hussain g , h , i , Daniel L. J. Thorek j , k , Michael J. Wolfgang c , g , and Ryan C. Riddle a
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Clinical, genetic, and structural basis of apparent mineralocorticoid excess due to 11{beta}-hydroxysteroid dehydrogenase type 2 deficiency [Medical Sciences]Mutations in 11β-hydroxysteroid dehydrogenase type 2 gene (HSD11B2) cause an extraordinarily rare autosomal recessive disorder, apparent mineralocorticoid excess (AME). AME is a form of low renin hypertension that is potentially fatal if untreated. Mutations in the HSD11B2 gene result either in severe AME or a milder phenotype (type 2 AME)....
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Human genetic variation alters CRISPR-Cas9 on- and off-targeting specificity at therapeutically implicated loci [Medical Sciences] Human genetic variation alters CRISPR-Cas9 on- and off-targeting specificity at therapeutically implicated loci Samuel Lessard a , b , Laurent Francioli c , d , Jessica Alfoldi c , d , Jean-Claude Tardif a , b , Patrick T. Ellinor d , e , Daniel G. MacArthur c , d , Guillaume Lettre a , b , Stuart H. Orkin f , g , h , i , j , 1 , and Matthew C. Canver f , g , h , i , 1 a Research Center, Montreal
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Impact of insecticide resistance in Anopheles arabiensis on malaria incidence and prevalence in Sudan and the costs of mitigation [Medical Sciences] Impact of insecticide resistance in Anopheles arabiensis on malaria incidence and prevalence in Sudan and the costs of mitigation Hmooda Toto Kafy a , b , 1 , Bashir Adam Ismail b , c , 1 , Abraham Peter Mnzava d , Jonathan Lines e , Mogahid Shiekh Eldin Abdin f , g , Jihad Sulieman Eltaher h , Anuar Osman Banaga i , Philippa West j , John Bradley j , Jackie Cook j , Brent Thomas k , Krishanthi S
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Proceedings of the National Academy of Sciences current issue
Identification of cancer genes that are independent of dominant proliferation and lineage programs [Medical Sciences] Identification of cancer genes that are independent of dominant proliferation and lineage programs Laura M. Selfors a , b , Daniel G. Stover a , b , c , 1 , Isaac S. Harris a , b , Joan S. Brugge a , b , 2 , and Jonathan L. Coloff a , b , 2 a Department of Cell Biology, Harvard Medical School , Boston, MA 02115; b Ludwig Center at Harvard, Harvard Medical School , Boston, MA 02115; c Department o
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Mechanism by which arylamine N-acetyltransferase 1 ablation causes insulin resistance in mice [Medical Sciences] Mechanism by which arylamine N -acetyltransferase 1 ablation causes insulin resistance in mice João Paulo Camporez a , 1 , Yongliang Wang a , 1 , Kasper Faarkrog a , b , Natsasi Chukijrungroat a , Kitt Falk Petersen a , b , and Gerald I. Shulman a , b , c , d , 2 a Department of Internal Medicine, Yale University School of Medicine , New Haven, CT 06520; b Novo Nordisk Center for Basic Metabolic
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Brain urea increase is an early Huntington’s disease pathogenic event observed in a prodromal transgenic sheep model and HD cases [Neuroscience] Brain urea increase is an early Huntington’s disease pathogenic event observed in a prodromal transgenic sheep model and HD cases Renee R. Handley a , 1 , Suzanne J. Reid a , 1 , Rudiger Brauning b , Paul Maclean b , Emily R. Mears a , Imche Fourie a , Stefano Patassini c , d , Garth J. S. Cooper a , d , Skye R. Rudiger e , Clive J. McLaughlan e , Paul J. Verma e , James F. Gusella f , Marcy E. M
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A transient dopamine signal encodes subjective value and causally influences demand in an economic context [Neuroscience] A transient dopamine signal encodes subjective value and causally influences demand in an economic context Scott A. Schelp a , Katherine J. Pultorak a , Dylan R. Rakowski a , Devan M. Gomez a , Gregory Krzystyniak a , Raibatak Das a , 1 , and Erik B. Oleson a , 2 a Psychology Department, University of Colorado Denver , Denver, CO 80217 Edited by Wolfram Schultz, University of Cambridge, Cambridge
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FKBP12 contributes to {alpha}-synuclein toxicity by regulating the calcineurin-dependent phosphoproteome [Neuroscience] FKBP12 contributes to α-synuclein toxicity by regulating the calcineurin-dependent phosphoproteome Gabriela Caraveo a , 1 , 2 , Martin Soste b , Valentina Cappelleti b , c , Saranna Fanning a , Damian B. van Rossum d , e , Luke Whitesell a , Yanmei Huang a , 3 , Chee Yeun Chung a , 4 , Valeriya Baru a , Sofia Zaichick f , Paola Picotti b , and Susan Lindquist a , g , h , 5 a Whitehead Institute f
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Noncanonical thyroid hormone signaling mediates cardiometabolic effects in vivo [Physiology] Author contributions: G.S.H. and L.C.M. designed research; G.S.H., H.R., J.L., X.-H.L., E.W., A.S.P., S.M.P., M.S.S., E.R., J.G., S.L., K.E., K.-H.S., D.Z., J.R., V.G.-D., H.F., M.H.d.A., L.K.-H., L.G., and L.C.M. performed research; S.M.P., M.S.S., P.K., J.R., V.G.-D., H.F., M.H.d.A., L.K.-H., J.K., D.L.A., L.G., J.H.D.B., G.R.W., and S.R. contributed new reagents/analytic tools; G.S.H., S.M.P.,
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Proceedings of the National Academy of Sciences current issue
Sex determination of human remains from peptides in tooth enamel [Anthropology] Sex determination of human remains from peptides in tooth enamel Nicolas Andre Stewart a , 1 , Raquel Fernanda Gerlach b , Rebecca L. Gowland c , Kurt J. Gron c , and Janet Montgomery c a School of Pharmacy and Biomolecular Sciences, University of Brighton , Brighton BN2 4AT, United Kingdom; b Department of Morphology, Physiology, and Basic Pathology, School of Dentistry of Ribeirão Preto, Univer
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PSMA-targeted polyinosine/polycytosine vector induces prostate tumor regression and invokes an antitumor immune response in mice [Applied Biological Sciences] PSMA-targeted polyinosine/polycytosine vector induces prostate tumor regression and invokes an antitumor immune response in mice Yael Langut a , Alaa Talhami b , 1 , Samarasimhareddy Mamidi b , Alexei Shir a , 2 , Maya Zigler a , 2 , Salim Joubran b , 3 , Anna Sagalov a , Efrat Flashner-Abramson a , 4 , Nufar Edinger a , Shoshana Klein a , and Alexander Levitzki a , 5 a Unit of Cellular Signaling
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Making two-photon processes dominate one-photon processes using mid-IR phonon polaritons [Applied Physical Sciences] Making two-photon processes dominate one-photon processes using mid-IR phonon polaritons Nicholas Rivera a , 1 , Gilles Rosolen a , b , John D. Joannopoulos a , 1 , Ido Kaminer a , c , and Marin Soljačić a a Department of Physics, Massachusetts Institute of Technology , Cambridge, MA 02139; b Micro- and Nanophotonic Materials Group, University of Mons , 7000, Mons, Belgium; c Department of Electr
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Distinct roles of N- and O-glycans in cellulase activity and stability [Biochemistry] Distinct roles of N- and O-glycans in cellulase activity and stability Antonella Amore a , 1 , Brandon C. Knott b , 1 , Nitin T. Supekar c , Asif Shajahan c , Parastoo Azadi c , Peng Zhao c , Lance Wells c , Jeffrey G. Linger b , Sarah E. Hobdey a , Todd A. Vander Wall a , Todd Shollenberger a , John M. Yarbrough a , Zhongping Tan d , e , Michael F. Crowley a , Michael E. Himmel a , Stephen R. De
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Kinetics of drug-ribosome interactions defines the cidality of macrolide antibiotics [Biochemistry] Kinetics of drug–ribosome interactions defines the cidality of macrolide antibiotics Maxim S. Svetlov a , Nora Vázquez-Laslop a , and Alexander S. Mankin a , 1 a Center for Biomolecular Sciences, University of Illinois at Chicago , Chicago, IL 60607 Edited by Peter B. Moore, Yale University, New Haven, CT, and approved November 20, 2017 (received for review October 3, 2017) Significance Ribosome-
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Structure-based prediction of ligand-protein interactions on a genome-wide scale [Biophysics and Computational Biology] Structure-based prediction of ligand–protein interactions on a genome-wide scale Howook Hwang a , b , c , d , Fabian Dey a , b , c , d , 1 , Donald Petrey a , b , c , d , and Barry Honig a , b , c , d , e , f , 2 a Department of Systems Biology, Columbia University , New York, NY 10032; b Center for Computational Biology and Bioinformatics, Columbia University , New York, NY 10032; c Department o
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Three tRNAs on the ribosome slow translation elongation [Biophysics and Computational Biology] Three tRNAs on the ribosome slow translation elongation Junhong Choi a , b and Joseph D. Puglisi b , 1 a Department of Applied Physics, Stanford University , Stanford, CA 94305; b Department of Structural Biology, Stanford University School of Medicine , Stanford, CA 94305 Contributed by Joseph D. Puglisi, November 10, 2017 (sent for review July 27, 2017; reviewed by Ruben L. Gonzalez Jr. and Mic
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Proceedings of the National Academy of Sciences current issue
Predicting glycosaminoglycan surface protein interactions and implications for studying axonal growth [Biophysics and Computational Biology] Predicting glycosaminoglycan surface protein interactions and implications for studying axonal growth Adam R. Griffith a , b , 1 , Claude J. Rogers b , 1 , Gregory M. Miller b , Ravinder Abrol a , b , Linda C. Hsieh-Wilson b , and William A. Goddard, III a , b , 2 a Materials and Process Simulation Center, California Institute of Technology , Pasadena, CA 91125; b Division of Chemistry and Chemic
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Structural studies of Chikungunya virus maturation [Biophysics and Computational Biology] Structural studies of Chikungunya virus maturation Moh Lan Yap a , b , Thomas Klose a , Akane Urakami c , S. Saif Hasan a , Wataru Akahata c , and Michael G. Rossmann a , 1 a Department of Biological Sciences, Purdue University , West Lafayette, IN 47907; b Department of Biological Science, Faculty of Science, Universiti Tunku Abdul Rahman , 31900 Kampar, Perak, Malaysia; c VLP Therapeutics , Gai
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Proceedings of the National Academy of Sciences current issue
Structural changes of tailless bacteriophage {Phi}X174 during penetration of bacterial cell walls [Biophysics and Computational Biology] Structural changes of tailless bacteriophage ΦX174 during penetration of bacterial cell walls Yingyuan Sun a , Aaron P. Roznowski b , Joshua M. Tokuda c , Thomas Klose a , Alexander Mauney c , Lois Pollack c , Bentley A. Fane b , and Michael G. Rossmann a , 1 a Department of Biological Sciences, Purdue University , West Lafayette, IN 47907; b The BIO5 Institute, University of Arizona , Tucson, AZ
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Network analysis identifies chromosome intermingling regions as regulatory hotspots for transcription [Biophysics and Computational Biology] Network analysis identifies chromosome intermingling regions as regulatory hotspots for transcription Anastasiya Belyaeva a , b , Saradha Venkatachalapathy c , Mallika Nagarajan c , G. V. Shivashankar c , d , and Caroline Uhler a , b , 1 a Laboratory for Information and Decision Systems, Massachusetts Institute of Technology, Cambridge, MA 02139; b Institute for Data, Systems, and Society, Massac
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Architecture of the human PI4KIII{alpha} lipid kinase complex [Cell Biology] Architecture of the human PI4KIIIα lipid kinase complex Joshua A. Lees a , 1 , Yixiao Zhang b , 1 , Michael S. Oh a , c , d , Curtis M. Schauder a , Xiaoling Yu e , 2 , Jeremy M. Baskin a , c , d , 3 , Kerry Dobbs f , Luigi D. Notarangelo f , Pietro De Camilli a , c , d , g , h , 4 , Thomas Walz b , 4 , and Karin M. Reinisch a , 4 a Department of Cell Biology, Yale University School of Medicine ,
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Proteasomes tether to two distinct sites at the nuclear pore complex [Cell Biology] Proteasomes tether to two distinct sites at the nuclear pore complex Sahradha Albert a , Miroslava Schaffer a , Florian Beck a , Shyamal Mosalaganti b , Shoh Asano a , 1 , Henry F. Thomas a , Jürgen M. Plitzko a , Martin Beck b , Wolfgang Baumeister a , 2 , and Benjamin D. Engel a , 2 a Department of Molecular Structural Biology, Max Planck Institute of Biochemistry , 82152 Martinsried, Germany;
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O-GlcNAcylation destabilizes the active tetrameric PKM2 to promote the Warburg effect [Cell Biology] O- GlcNAcylation destabilizes the active tetrameric PKM2 to promote the Warburg effect Yang Wang a , 1 , Jia Liu a , 1 , Xin Jin a , 1 , Dapeng Zhang b , c , Dongxue Li a , Fengqi Hao a , Yunpeng Feng a , Shan Gu a , Fanlin Meng a , Miaomiao Tian a , Yi Zheng a , Ling Xin a , Xinbo Zhang a , Xue Han a , L. Aravind d , and Min Wei a , 2 a Key Laboratory of Molecular Epigenetics of the Ministry of
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A small-molecule activator of kinesin-1 drives remodeling of the microtubule network [Cell Biology] A small-molecule activator of kinesin-1 drives remodeling of the microtubule network Thomas S. Randall a , Yan Y. Yip a , Daynea J. Wallock-Richards a , Karin Pfisterer a , Anneri Sanger a , Weronika Ficek a , Roberto A. Steiner a , Andrew J. Beavil a , Maddy Parsons a , and Mark P. Dodding a , b , 1 a Randall Centre for Cell and Molecular Biophysics, King’s College London , London SE1 1UL, Unite
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Ultrafast rotation in an amphidynamic crystalline metal organic framework [Chemistry] Ultrafast rotation in an amphidynamic crystalline metal organic framework Cortnie S. Vogelsberg a , Fernando J. Uribe-Romo b , Andrew S. Lipton c , Song Yang a , K. N. Houk a , Stuart Brown d , and Miguel A. Garcia-Garibay a , 1 a Department of Chemistry and Biochemistry, University of California, Los Angeles , CA 90095; b Department of Chemistry, University of Central Florida , Orlando, FL 32816
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Autocatalytic surface reduction and its role in controlling seed-mediated growth of colloidal metal nanocrystals [Chemistry] Autocatalytic surface reduction and its role in controlling seed-mediated growth of colloidal metal nanocrystals Tung-Han Yang a , b , Shan Zhou c , Kyle D. Gilroy a , Legna Figueroa-Cosme c , Yi-Hsien Lee b , Jenn-Ming Wu b , and Younan Xia a , c , d , 1 a The Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University , Atlanta, GA 30332; b Depa
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SE2 reaction in noncarbon system: Metal-halide catalysis for dehydrogenation of ammonia borane [Chemistry] S E 2 reaction in noncarbon system: Metal-halide catalysis for dehydrogenation of ammonia borane Sung Jin Pai a and Sang Soo Han a , 1 a Computational Science Research Center, Korea Institute of Science and Technology , Seongbuk-gu, Seoul 136-791, Republic of Korea Edited by Jerrold Meinwald, Cornell University, Ithaca, NY, and approved November 15, 2017 (received for review July 7, 2017) Signifi
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Allosteric histidine switch for regulation of intracellular zinc(II) fluctuation [Chemistry] Allosteric histidine switch for regulation of intracellular zinc(II) fluctuation Rongfeng Zhu a , b , c , 1 , Yanqun Song a , 1 , Haiping Liu d , 1 , Yufei Yang e , Shenlin Wang e , Chengqi Yi b , f , and Peng R. Chen a , b , 2 a Synthetic and Functional Biomolecules Center, Beijing National Laboratory for Molecular Sciences, Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Min
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Machine learning shows association between genetic variability in PPARG and cerebral connectivity in preterm infants [Developmental Biology] Machine learning shows association between genetic variability in PPARG and cerebral connectivity in preterm infants Michelle L. Krishnan a , Zi Wang b , Paul Aljabar a , Gareth Ball a , Ghazala Mirza c , Alka Saxena c , Serena J. Counsell a , Joseph V. Hajnal a , b , Giovanni Montana b , 1 , and A. David Edwards a , 1 , 2 a Centre for the Developing Brain, King’s College London, St. Thomas’ Hosp
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Naturalization of European plants on other continents: The role of donor habitats [Ecology] Naturalization of European plants on other continents: The role of donor habitats Veronika Kalusová a , 1 , Milan Chytrý a , Mark van Kleunen b , c , Ladislav Mucina d , e , Wayne Dawson f , Franz Essl g , Holger Kreft h , Jan Pergl i , Patrick Weigelt h , Marten Winter j , and Petr Pyšek i , k , l a Department of Botany and Zoology, Masaryk University , 611 37 Brno, Czech Republic; b Ecology Lab
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Critical dynamics in population vaccinating behavior [Ecology] Critical dynamics in population vaccinating behavior A. Demetri Pananos a , Thomas M. Bury a , Clara Wang b , Justin Schonfeld a , Sharada P. Mohanty c , Brendan Nyhan b , Marcel Salathé c , and Chris T. Bauch a , 1 a Department of Applied Mathematics, University of Waterloo , Waterloo, ON, Canada N2L 3G1; b Department of Government, Dartmouth College , Hanover, NH 03755; c Digital Epidemiology L
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Understanding the mechanisms of amorphous creep through molecular simulation [Engineering] Understanding the mechanisms of amorphous creep through molecular simulation Penghui Cao a , Michael P. Short a , and Sidney Yip a , b , 1 a Department of Nuclear Science and Engineering, Massachusetts Institute of Technology , Cambridge, MA 02139; b Department of Materials Science and Engineering, Massachusetts Institute of Technology , Cambridge, MA 02139 Edited by Sharon C. Glotzer, University
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Single-cell analysis resolves the cell state transition and signaling dynamics associated with melanoma drug-induced resistance [Engineering] Single-cell analysis resolves the cell state transition and signaling dynamics associated with melanoma drug-induced resistance Yapeng Su a , b , 1 , Wei Wei a , c , d , 1 , 2 , Lidia Robert e , 1 , Min Xue a , b , Jennifer Tsoi c , Angel Garcia-Diaz e , Blanca Homet Moreno e , f , Jungwoo Kim a , b , Rachel H. Ng a , b , Jihoon W. Lee a , b , Richard C. Koya g , Begonya Comin-Anduix d , g , Thom
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Proceedings of the National Academy of Sciences current issue
Opinion: Why we need a National Living Soil Repository [Environmental Sciences] Opinion: Why we need a National Living Soil Repository Daniel K. Manter a , Jorge A. Delgado a , 1 , Harvey D. Blackburn b , Daren Harmel c , Adalberto A. Pérez de León d , e , and C. Wayne Honeycutt f a Soil Management and Sugar Beet Research Unit, United States Department of Agriculture–Agricultural Research Service, Fort Collins, CO 80526; b National Laboratory for Genetic Resources Preservati
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Proceedings of the National Academy of Sciences current issue
Earliest hydraulic enterprise in China, 5,100 years ago [Environmental Sciences] Earliest hydraulic enterprise in China, 5,100 years ago Bin Liu a , Ningyuan Wang a , Minghui Chen a , Xiaohong Wu b , Duowen Mo c , Jianguo Liu d , Shijin Xu e , and Yijie Zhuang f , 1 a Prehistoric Department, Zhejiang Provincial Institute of Cultural Relics and Archaeology , 310014 Hangzhou, China; b School of Archaeology and Museology, Peking University , 100871 Beijing, China; c College of U
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Dispersal limitation promotes the diversification of the mammalian gut microbiota [Evolution] Dispersal limitation promotes the diversification of the mammalian gut microbiota Andrew H. Moeller a , b , c , 1 , Taichi A. Suzuki b , c , Dana Lin b , c , Eileen A. Lacey b , c , Samuel K. Wasser d , and Michael W. Nachman b , c a Miller Institute for Basic Research in Science, University of California, Berkeley , CA 94720; b Museum of Vertebrate Zoology, University of California , Berkeley, C
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Resource limitation prevents the emergence of drug resistance by intensifying within-host competition [Evolution] Resource limitation prevents the emergence of drug resistance by intensifying within-host competition Nina Wale a , 1 , 2 , Derek G. Sim a , Matthew J. Jones a , Rahel Salathe a , Troy Day b , c , and Andrew F. Read a , d a Center for Infectious Disease Dynamics, Department of Biology, The Pennsylvania State University , University Park, PA 16802; b Department of Mathematics and Statistics, Queen
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Epigenetic control of pheromone MAPK signaling determines sexual fecundity in Candida albicans [Genetics] Epigenetic control of pheromone MAPK signaling determines sexual fecundity in Candida albicans Christine M. Scaduto a , 1 , Shail Kabrawala a , Gregory J. Thomson a , William Scheving a , Andy Ly a , Matthew Z. Anderson a , 2 , Malcolm Whiteway b , and Richard J. Bennett a , 3 a Department of Molecular Microbiology and Immunology, Brown University , Providence, RI 02912; b Department of Biology,
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Cytokine signaling through Drosophila Mthl10 ties lifespan to environmental stress [Immunology and Inflammation] Cytokine signaling through Drosophila Mthl10 ties lifespan to environmental stress Eui Jae Sung a , Masasuke Ryuda b , Hitoshi Matsumoto c , Outa Uryu c , Masanori Ochiai d , Molly E. Cook e , Na Young Yi f , Huanchen Wang a , James W. Putney g , Gary S. Bird g , Stephen B. Shears a , 1 , and Yoichi Hayakawa c , 1 a Inositol Signaling Group, Signal Transduction Laboratory, National Institute of E
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Interferon-beta represses cancer stem cell properties in triple-negative breast cancer [Medical Sciences] Interferon-beta represses cancer stem cell properties in triple-negative breast cancer Mary R. Doherty a , 1 , HyeonJoo Cheon b , Damian J. Junk a , c , Shaveta Vinayak c , d , e , Vinay Varadan c , f , Melinda L. Telli g , James M. Ford g , George R. Stark b , c , 1 , and Mark W. Jackson a , c , 1 a Department of Pathology, Case Western Reserve University , School of Medicine, Cleveland, OH 4410
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Early endosome as a pathogenic target for antiphosphatidylethanolamine antibodies [Medical Sciences] Early endosome as a pathogenic target for antiphosphatidylethanolamine antibodies Songwang Hou a , Heike Fölsch b , Ke Ke a , Joan Cook Mills c , Rosalind Ramsey-Goldman d , and Ming Zhao a , 1 a Feinberg Cardiovascular Research Institute, Department of Medicine, Northwestern University , Chicago, IL 60611; b Department of Cell and Molecular Biology, Northwestern University , Chicago, IL 60611; c
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Obligatory role of hypothalamic neuroestradiol during the estrogen-induced LH surge in female ovariectomized rhesus monkeys [Medical Sciences] Obligatory role of hypothalamic neuroestradiol during the estrogen-induced LH surge in female ovariectomized rhesus monkeys Brian P. Kenealy a , Kim L. Keen a , James P. Garcia a , Lucille K. Kohlenberg a , and Ei Terasawa a , b , 1 a Wisconsin National Primate Research Center, University of Wisconsin–Madison , Madison, WI 53715; b Department of Pediatrics, University of Wisconsin–Madison , Madis
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Beta oscillations reflect supramodal information during perceptual judgment [Neuroscience] Beta oscillations reflect supramodal information during perceptual judgment Saskia Haegens a , b , 1 , José Vergara c , Román Rossi-Pool c , Luis Lemus c , and Ranulfo Romo c , d , 1 a Department of Neurosurgery, Columbia University Medical Center , New York, NY 10032; b Donders Institute for Brain, Cognition and Behaviour, Radboud University Nijmegen , 6500HB Nijmegen, The Netherlands; c Institu
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Appetite suppressive role of medial septal glutamatergic neurons [Neuroscience] Appetite suppressive role of medial septal glutamatergic neurons Patrick Sweeney a , Changhong Li a , b , and Yunlei Yang a , c , d , 1 a Department of Neuroscience and Physiology, State University of New York Upstate Medical University , Syracuse, NY 13210; b Department of Neurology, Beijing Haidian Hospital , Beijing, 100080, People’s Republic of China; c Division of Endocrinology and Diabetes,
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De novo reconstitution reveals the proteins required for skeletal muscle voltage-induced Ca2+ release [Physiology] De novo reconstitution reveals the proteins required for skeletal muscle voltage-induced Ca 2+ release Stefano Perni a , Manuela Lavorato b , and Kurt G. Beam a , 1 a Department of Physiology and Biophysics, Anschutz Medical Campus, University of Colorado , Aurora, CO 80045; b Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania , Philadelphia, PA
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Accelerating fishes increase propulsive efficiency by modulating vortex ring geometry [Physiology] Accelerating fishes increase propulsive efficiency by modulating vortex ring geometry Otar Akanyeti a , b , 1 , Joy Putney a , c , Yuzo R. Yanagitsuru a , George V. Lauder d , William J. Stewart a , e , and James C. Liao a , 1 a The Whitney Laboratory for Marine Bioscience, Department of Biology, University of Florida , St. Augustine, FL 32080; b The Department of Computer Science, Aberystwyth Un
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Ethylene promotes root hair growth through coordinated EIN3/EIL1 and RHD6/RSL1 activity in Arabidopsis [Plant Biology] Ethylene promotes root hair growth through coordinated EIN3/EIL1 and RHD6/RSL1 activity in Arabidopsis Ying Feng a , b , Ping Xu b , Bosheng Li a , Pengpeng Li b , Xing Wen a , Fengying An b , Yan Gong b , Yi Xin b , Ziqiang Zhu b , c , Yichuan Wang a , 1 , and Hongwei Guo a , d , 1 a Institute of Plant and Food Science, Department of Biology, Southern University of Science and Technology , Shenz
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Perception and misperception of surface opacity [Psychological and Cognitive Sciences] Perception and misperception of surface opacity Phillip J. Marlow a , 1 , Juno Kim b , and Barton L. Anderson a , 1 a School of Psychology, University of Sydney , NSW 2006, Sydney, Australia; b School of Optometry and Vision Science, NSW 2052, Sydney, Australia Edited by Wilson S. Geisler, University of Texas at Austin, Austin, TX, and approved November 7, 2017 (received for review June 29, 2017)
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Default neglect in attempts at social influence [Psychological and Cognitive Sciences] Default neglect in attempts at social influence Julian J. Zlatev a , 1 , David P. Daniels b , Hajin Kim c , and Margaret A. Neale a a Graduate School of Business, Stanford University , Stanford, CA 94305; b School of Business and Management, The Hong Kong University of Science and Technology , Hong Kong; c School of Earth, Energy & Environmental Sciences, Stanford University , Stanford, CA 94305
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Human presence diminishes the importance of climate in driving fire activity across the United States [Sustainability Science] Human presence diminishes the importance of climate in driving fire activity across the United States Alexandra D. Syphard a , 1 , Jon E. Keeley b , c , Anne H. Pfaff b , and Ken Ferschweiler a a Conservation Biology Institute , Corvallis, OR 97333; b US Geological Survey , Western Ecological Research Center, Sequoia-Kings Canyon Field Station, Three Rivers, CA 93271; c Department of Ecology & Ev
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Correction for Waldrop, News Feature: The genuine problem of fake news [Correction]NEWS FEATURE Correction for “News Feature: The genuine problem of fake news,” by M. Mitchell Waldrop, which was first published November 16, 2017; 10.1073/pnas.1719005114 (Proc Natl Acad Sci USA 114:12631–12634). The editors note that on page 12632, right column, first paragraph, lines 4–7, “Dan Gillmor, a technology writer who heads...
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Correction for Roehr, Core Concept: Tissue resident memory cells emerging as key player in health and disease [Correction]CORE CONCEPTS Correction for “Core Concept: Tissue resident memory cells emerging as key player in health and disease,” by Bob Roehr, which was first published November 14, 2017; 10.1073/pnas.1715754114 (Proc Natl Acad Sci USA 114:12092–12093). The editors note that reference 3 appeared incorrectly. The complete corrected reference appears below. The...
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Proceedings of the National Academy of Sciences current issue
Correction for Possner and Caldeira, Geophysical potential for wind energy over the open oceans [Correction]ENVIRONMENTAL SCIENCES, SUSTAINABILITY SCIENCE Correction for “Geophysical potential for wind energy over the open oceans,” by Anna Possner and Ken Caldeira, which was first published October 9, 2017; 10.1073/pnas.1705710114 (Proc Natl Acad Sci USA 114:11338–11343). The authors note that Fig. 6 appeared incorrectly. The corrected figure and its legend appear...
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Proceedings of the National Academy of Sciences current issue
Retraction for Ottmann et al., Long-term aggregation of larval fish siblings during dispersal along an open coast [Retractions] Retraction for Ottmann et al., Long-term aggregation of larval fish siblings during dispersal along an open coast ECOLOGY Retraction for “Long-term aggregation of larval fish siblings during dispersal along an open coast,” by Daniel Ottmann, Kirsten Grorud-Colvert, Nicholas M. Sard, Brittany E. Huntington, Michael A. Banks, and Su Sponaugle, which was first published November 21, 2016; 10.1073/pn
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Live Science
Footstrike Hemolysis: How Running Changed One Man's Blood Cells Running long distances can be hard on the body, but as one ultramarathoner found out, it can also take a toll on an individual's red blood cells. According to a recent case report, all the pounding that happens when a runner's feet hits the pavement could directly injure that person's red blood cells. In the case, which was published Dec. 13 in the journal BMJ Case Reports , a 41-year-o
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Big Think
This Is How Much the Most Profitable U.S. Corporations Make a Second Neil DeGrasse Tyson noted in 2014 that if Bill Gates was walking down the street and saw money on the ground, if it was any less than $45,000 he’d actually be losing money to stop and pick it up. That’s how fast his wealth accumulates. (This was 2014, mind you, so who knows how much that figure would be now.) While not quite in Gates’ bracket, the same idea applies to a number of corporations, wh
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The Atlantic
A Memorable Mother-Daughter Talk in Lady Bird Over the next month, The Atlantic’s “And, Scene” series will delve into some of the most interesting films of the year by examining a single, noteworthy moment and unpacking what it says about 2017. Next up is Greta Gerwig’s Lady Bird . (Read our previous entries here .) There’s an appreciable freneticism to Lady Bird , Greta Gerwig’s wonderful coming-of-age dramedy about a 17-year-old girl (Saoi
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EurekAlert! - Breaking News
Befriending oneself has benefits, but backup plan recommended PULLMAN, Wash.- As weird animals go, the mangrove killifish is in a class of its own. It flourishes in both freshwater and water with twice as much salt as the ocean. It can live up to two months on land, breathing through its skin, before returning to the water with a series of spectacular 180-degree flips. And it is one of only two vertebrates -- the other is a close relative -- that fertilizes
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EurekAlert! - Breaking News
New laws increase access to healthcare delivery for advanced practice registered nurses December 26, 2017 - As 2017 comes to a close, many states have enacted laws and regulations expanding access to healthcare provided by advanced practice registered nurses (APRNs), according to the 30th Annual Legislative Update in the January issue of The Nurse Practitioner , published by Wolters Kluwer . "In 2017, over 20 states reported passage of legislation positively impacting access to an
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EurekAlert! - Breaking News
The scientists from MSU developed a basis for highly sensitive gas sensors IMAGE: Principle of the operation of the sensor based on porous silicon nanowire arrays. view more Credit: Liubov Osminkina A team from the Faculty of Physics of Lomonosov Moscow State University suggested using porous silicon nanowire arrays in highly sensitive gas sensors. These devices will be able to detect the presence of toxic and non-toxic gas molecules in the air at room temperature.
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Phys.org - latest science and technology news stories
Scientists should be super modelers A young panda in Wolong Nature Reserve relaxes in a tree. Young pandas get a lot of tree time. Credit: Sue Nichols, Michigan State University Center for Systems Integration and Sustainability Scholars and conservationists want to aim for the right future to preserve biodiversity and plan sustainable environments. One of those scholars is calling for due diligence to make sure the right data, not
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EurekAlert! - Breaking News
Toward designing/controlling flexibility of MOFs IMAGE: Flexible metal-organic frameworks: from controlling the structures to controlling the flexibility. view more Credit: ©Science China Press Porous coordination polymers (PCPs) or metal-organic frameworks (MOFs) have been extensively studied for their diversified and designable/tailorable framework and pore structures. Compared with conventional porous materials, MOFs have much larger fra
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EurekAlert! - Breaking News
Scientists should be super modelers IMAGE: A young panda in Wolong Nature Reserve relaxes in a tree. Young pandas get a lot of tree time. view more Credit: Sue Nichols, Michigan State University Center for Systems Integration and Sustainability Scholars and conservationists want to aim for the right future to preserve biodiversity and plan sustainable environments. One of those scholars is calling for due diligence to make sure the
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EurekAlert! - Breaking News
Thermoelectric power generation at room temperature: Coming soon? IMAGE: (a) Three-dimensional crystal structure of YbSi2, (b) view along the a-axis, and (c) along the c-axis. view more Credit: © 2017 Kurosaki et al. Phys. Status Solidi RRL 2017, 1700372. doi: 10.1002/pssr.201700372 Osaka - Thermoelectric (TE) materials could play a key role in future technologies. Although the applications of these remarkable compounds have long been explored, they are
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EurekAlert! - Breaking News
Human influences have reduced the likelihood of record-breaking cold event in China It is controversial whether Eurasian mid-latitude cold surges are becoming more likely as a consequence of Arctic warming. A strong cold surge occurred during 21st-25th January 2016 affecting most areas of China, especially Eastern China. Daily minimum temperature records were broken at many stations. The area averaged anomaly of minimum temperature over the region (20-44oN, 100-124oE) for this p
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Phys.org - latest science and technology news stories
Military turns to oyster reefs to protect against storms Earle Naval Weapons Station, where the Navy loads some of America's most sophisticated weapons onto warships, suffered $50 million worth of damage in Superstorm Sandy. Now the naval pier is fortifying itself with some decidedly low-tech protection: oysters. The facility has allowed an environmental group to plant nearly a mile of oyster reefs about a quarter-mile off its shoreline to serve as a n
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Phys.org - latest science and technology news stories
Satellite keeps an eye on US holiday travel weather This visible image of the US was captured from NOAA's GOES-East satellite on Friday, Dec. 22 at 1902 UTC (2:02 p.m. EST). Credit: NOAA A satellite view of the U.S. on Dec. 22 revealed holiday travelers on both coasts are running into wet weather. A visible image from NOAA's GOES-16 satellite showed systems affecting the Pacific Northwest, the Ohio and Tennessee Valleys and the areas from the sout
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EurekAlert! - Breaking News
A powerful guiding principle for topological quantum synthesis IMAGE: The collaborative team of Prof. Huijun Liu at Wuhan University, Prof. Xingqiu Chen at the Institute of Metal Research, Chinese Academy of Sciences, and Prof. Zhenyu Zhang at the University... view more Credit: ©Science China Press Topological materials are a new, rapidly expanding family of quantum matter, which can be classified into topological insulators (TIs), topological crystalli
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EurekAlert! - Breaking News
A new strategy for efficient hydrogen production A joint research team, affiliated with UNIST has introduced the Hybrid-Solid Electrolysis Cell (Hybrid-SOEC) system with highest reported electrochemical performance in hydrogen production. The proposed system has attracted much attention as a new promising option for the cost-effective and highly-efficient hydrogen production, as it shows excellent performance compared with other wat
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EurekAlert! - Breaking News
New strategy for isotope separation with flexible porous material A new study by an international team of researchers, affiliated with UNIST has announced that they have succeeded in developing a novel deuterium separation method, using a special class of metal organic frameworks (MOFs) whose pore dimensions change upon gas adsorption. This new strategy allows 'deuterium (Chemical symbol D or 2H)' to diffuse more quickly through the expanded pores of MO
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EurekAlert! - Breaking News
NTU study finds that hackers could guess your phone PIN using its sensor data p>Singapore, 26 Dec 2017 NTU study finds that hackers could guess your phone PIN using its sensor data Data from the physical sensors in a smart phone could be used by hackers to guesacs the security PIN and unlock it. Instruments in smart phones such as the accelerometer, gyroscope and proximity sensors represent a potential security vulnerability, according to researchers from Nanyang Technolog
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New Scientist - News
The universe may be full of ex-moons flung from their homeworlds Chaos in stellar systems can turn exomoons into ex-moons Getty By John Wenz The cosmos may be awash in wandering, lonesome former moons, ejected from their respective planetary systems long ago. Nobody has ever conclusively seen a moon orbiting a planet in another stellar system , partly because their small size and great distance makes them difficult to find with modern detection methods. Bu
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Phys.org - latest science and technology news stories
Dietary restriction and life span in male and hermaphrodite worms Microscopy image of a hermaphrodite C. elegans . Credit: Nishida Lab An organism's lifespan is known to be affected by its sex and diet, but where these two factors overlap biologically is not well understood. Researchers in Japan looked for clues in worms— C. elegans —that have two sexes: hermaphrodite or male. They found that hermaphrodite worms can live over two weeks longer when put on variou
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EurekAlert! - Breaking News
Mass spectrometric imaging technique makes diagnosis easier and smarter A research team of New Biology at DGIST has recently developed a technology which enables to acquire a high resolution mass spectrometry imaging in micrometer size of live biological samples without chemical pretreatment in the general atmospheric pressure environment. This achievement has been led by Professor Dae Won Moon and Dr. Jae Young Kim from the department of New Biology at DGI
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EurekAlert! - Breaking News
Understanding the molecular mechanisms of ALS Scientists have revealed more details of the molecular mechanism behind neuronal cell death in amyotrophic lateral sclerosis (ALS), a step forward to find ways to control progression of the disease. Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, is a fatal neurological disease that causes death of the motor neurons that control muscles in the body. There are currently no
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EurekAlert! - Breaking News
CD4 T cells, xenobiotic transporters, and metabolites in inflammatory bowel diseases IMAGE: Mdr1 induced by CD103+ DCs mediates maintenance of intestinal T cell homeostasis in the presence of bile acids. view more Credit: Osaka University Osaka - Our immune system protects our bodies from numerous pathogenic microbes and toxins in the environment. The system comprises innate (non-specific) and adaptive (acquired) immunity. When innate immune cells recognize pathogens, the
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EurekAlert! - Breaking News
Development of a nanowire device to detect cancer with a urine test Researchers centered at Nagoya University develop a nanowire device able to detect microscopic levels of urinary markers potentially implicated in cancer Nagoya, Japan - Cells communicate with each other through a number of different mechanisms. Some of these mechanisms are well-known: in animals, for example, predatory threats can drive the release of norepinephrine, a hormone that travels throu
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Live Science
Buttless Wonder: New Worm Has No Anus Scientists studying the seafloor off Japan recently discovered a new worm, Xenoturbella japonica , that has no anus. Credit: University of Tsukuba A bizarre new species of marine worm lacks a number of internal features common to other animals — including an anus, new research shows. The strange, pale-orange creature, scientifically known as Xenoturbella japonica , was found on the seafloor
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BBC News - Science & Environment
Sea smoke phenomenon on Lake Superior, MinnesotaFootage captures the Christmas Day scene over Lake Superior, US.
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Futurity.org
Eating fish linked to better sleep and higher I.Q. for kids Kids who eat fish at least once a week sleep better and have IQ scores that are 4 points higher, on average, than those who eat fish less frequently or not at all, a new study shows. Previous studies showed a relationship between omega-3s, the fatty acids in many types of fish, and improved intelligence, as well as omega-3s and better sleep. But researchers hadn’t connected all three before. The
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EurekAlert! - Breaking News
Technique to allow AI to learn words in the flow of dialogue developed IMAGE: Example of implicit confirmation: 1. Predict category of unknown word. 2. Generate implicit confirmation request with category c. 3. Determine if the category c is correct from user response. view more Credit: Osaka University A group of researchers at Osaka University has developed a new method for dialogue systems*1. This new method, lexical acquisition through implicit confirmat
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EurekAlert! - Breaking News
Traditional secrets to keeping cool: Investigating Okinawan textiles IMAGE: Toshiko Taira, a living national treasure who made great efforts in the conservation of Basho-fu for the Kijoka Basho-fu Association, was herself certified as an Important Intangible Cultural Heritage.... view more Credit: Kijoka Basho-fu Association When Yoko Nomura moved from warm, dry California to the subtropical island of Okinawa, she was struck by the stifling heat and hu
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Popular Science
Mysterious double 'whirlpools' are popping up in the ocean Scientists have spotted a bizarre phenomenon reeling through the southern seas: linked swirls of water that resemble giant whirlpools spinning in opposite directions. Rotating masses of water called eddies are common in the ocean. The newly revealed pairs, however, churn through the water up to ten times faster than their single counterparts, and are connected underwater by a U-shaped vortex. Wha
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Futurity.org
‘Tags’ sewn into clothes could monitor vital signs A new system for monitoring vital signs like blood pressure, heart rate, and breath rate uses a cheap and covert system of radio-frequency signals and microchip “tags,” similar to the anti-theft tags department stores place on clothes and electronics to prevent shoplifting. The cracker-sized tags measure mechanical motion by emitting radio waves that bounce off the body and internal organs, which
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EurekAlert! - Breaking News
Social interactions override genetics when birds learn new songs New UC San Francisco research finds that although young male songbirds are genetically predisposed to sound like their fathers, enriched early experience with a foster-father can overcome this genetic destiny. This finding has striking implications for our thinking about how experience influences the genetics of complex human traits like learning ability or even psychiatric disease, the authors s
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Live Science
60-Million-Year-Old Meteor Strike Uncovered on Remote Isle of Skye A thin slice of ejecta deposited on the Isle of Skye, Scotland, 60 million years ago. Credit: Simon Drake A remote island in Scotland bears traces of out-of-this-world minerals from a 60-million-year-old meteorite impact. A team of geologists from Birkbeck, University of London was examining volcanic rocks on the remote Isle of Skye in Scotland when they uncovered rare minerals that have ne
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Live Science
WWI-Era Submarine Found in Remote Waters off Papua New Guinea The HMAS AE1 was discovered off the coast of Papua New Guinea, 103 years after it vanished beneath the waves. Credit: © Commonwealth of Australia A downed navy submarine that vanished 103 years ago was recently discovered in the remote ocean area around Papua New Guinea. The Australian Navy submarine HMAS AE1 was discovered near the Duke of York Islands off Papua New Guinea roughly 1,000 fe
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Blog » Languages » English
Summer vs Winter: Battle of the Seasons It’s getting cold outside, and it’s time for a great seasonal battle. Are you loving this chilly weather, or are you thinking of a cool drink on the beach to get you through the season? Make your choice and let the battle begin! Summer Summer is the hottest of the 4 temperate seasons. At the height of summer is the summer solstice, where the days are longest and the nights are shortest for the ye
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EurekAlert! - Breaking News
Satellite keeps an eye on US holiday travel weather A satellite view of the U.S. on Dec. 22 revealed holiday travelers on both coasts are running into wet weather. A visible image from NOAA's GOES-16 satellite showed systems affecting the Pacific Northwest, the Ohio and Tennessee Valleys and the areas from the southeastern U.S. to the Mid-Atlantic. NOAA's GOES-East satellite provides infrared and visible data of the eastern half of the U.S. In a v
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EurekAlert! - Breaking News
Pulmonary fibrosis caused by single transcription factor To date, the molecular basis of pulmonary fibrosis has been poorly understood. Scientists from the Max Planck Institute for Heart and Lung Research in Bad Nauheim have now shown that reduced activity of the transcription factor FoxO3 plays a key role in the development of the disease. In research on mice, the progress of the disease was able to be halted using drugs that boost FoxO3 activity. The
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Phys.org - latest science and technology news stories
Is online college for you? Answer five questions to find out In this Dec. 20, 2013, file photo, patrons of the Hernando, Miss., branch of First Regional Library system explore online college-level courses that can earn credit. Prospective students who want a college degree but can't attend a traditional campus may consider online college for its flexibility and independent learning style. But self-paced courses are not for everyone. (Stan Carroll/The Comme
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Feed: All Latest
The Most-read WIRED Gear Stories of 2017 There's no denying it. WIRED readers love stories of the pomaceous variety. News about Apple or Apple products accounted for half a dozen of our 17 most-read Gear stories of the year, and for good reason: this year, the company celebrated the ten-year anniversary of the iPhone, the personal product that inarguably changed the world. Apple marked the occasion by releasing the iPhone X , a device d
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Big Think
If the Pentagon Is Hiding Aliens from Us, the Zoo Hypothesis May Explain Why Recent revelations that the Pentagon had an actual alien-hunting division have rocked conspiracy theorists everywhere, adding fuel to the long-held beliefs of many that the government is hiding the truth from us. Luis Elizondo , the military intel official who headed the now-defunct “Advanced Aviation Threat Identification Program,” which ran from 2009 until 2012, was so convinced by what he saw
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Popular Science
This holiday season, fix your loved one's computer without having to visit them You're at a family gathering when your grandparents start talking about their computer issues. Stop avoiding eye contact—you can troubleshoot whatever problem they might have from the comfort of your own desk chair. When you download a screen sharing application to multiple machines, the software lets you access one computer while seated at another. This comes in handy if you want to help friends
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Live Science
This Tiny Sea Monster Had Creepy Mouth Appendages Artistic reconstruction of the tiny sea predator Habelia optata . Credit: Joanna Liang/Royal Ontario Museum When Habelia optata first skittered into public consciousness more than a century ago, scientists didn't know what to make of it. The long-extinct sea predator, which flourished during the middle Cambrian period about 508 million years ago, measured less than a inch long, yet it wasn't an
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Futurity.org
We tend to inflate our negative feelings in surveys People tend to overstate their negative feelings and symptoms in surveys, a new study suggests. This bias wears off over time, but the results point to the possibility that measurements of health and well-being, which are vital in making medical assessments and in guiding health-related research, may be misinterpreted. “Understanding the magnitude of this bias is essential in accurately interpret
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Live Science
Photos: Prehistoric Rock Art Hints at Elite Class on Kisar On Kisar Credit: Sue O'Connor/ANU Near Timor Credit: Sue O'Connor/ANU Rich history Credit: Sue O'Connor/ANU An ocean view Credit: Sue O'Connor/ANU Evidence of humanity Credit: Sue O'Connor/ANU Doodles Credit: Sue O'Connor/ANU Pet art Credit: Sue O'Connor/ANU Rock art Credit: Sue O'Connor/ANU Cultural changes Credit: Sue O'Connor/ANU Trade influence Credit: Sue O'Connor/ANU Important images Credit
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Live Science
Prehistoric Rock Art Found on Tiny Indonesian Island Looking like a prehistoric art gallery, rock paintings depicting dogs, horses, boats and processions of people decorate the walls and ceilings of limestone overhangs on a tiny island in Indonesia, scientists have found. Though art lovers may not have visited the gorgeous exhibits in a formal sense, the paintings — most of which were created around 2,500 years ago — may be a sign of the emer
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The Atlantic
Can Non-Billionaires Make a Difference in Conservation? An Example From Europe Late last week, I mentioned a historically large conservation gift, worth $165 million and coming from one of America’s successful tech-industry families, that will preserve more than 24,000 acres of historically significant, aesthetically beautiful, and ecologically important coastland around Point Conception, California. Part of the idea behind this gift, from Jack and Laura Dangermond of the E
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Feed: All Latest
2017 Was The Year We Fell Out of Love with Algorithms We owe a lot to 9th century Persian scholar Muhammad ibn Musa al-Khwarizmi. Centuries after his death, al-Khwarizmi's works introduced Europe to decimals and algebra, laying some of the foundations for today’s techno-centric age. The latinized version of his name has become a common word: algorithm. In 2017, it took on some sinister overtones. Take this exchange from the US House Intelligence Com
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NYT > Science
Global Health: Measles Deaths Fall to a Record Low Worldwide “Sadly, this excellent progress threatens to be undermined by low coverage, not only in many developing countries, but also in some wealthy ones ,” Dr. Seth Berkley, Gavi’s chief executive officer, said in his year-end letter . Because measles is so contagious — one child can infect a dozen others in a classroom or at a playground, even before the telltale rash appears — outbreaks in any communit
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The Atlantic
Bitcoin 'Is Just Like the Dot-Com Bubble' What is bitcoin? An investment? A technology? A bubble? What is even happening? All of these questions seem like reasonable ones to ask, as its price has surged and plummeted. Bitcoin is many things: a proxy for more stable units like the dollar and the euro, a speculative investment , a payments mechanism, a means of hiding transactions from various governments and tax collectors, and a monetary
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Ingeniøren
De valgte at se fiaskoen i øjnene I mandags pakkede Mads Rømer Svendsen drømmen om egen virksomhed ned i flyttekasser og forlod sammen med sine to kompagnoner iværksættermiljøet Danish Tech Challenge på DTU, som de har været en del af siden september. Resterne af trekløverets firma, Sentar, står nu pakket samme i det kælderlokale på Østerbro i København, hvor det hele begyndte i februar 2016. Men intet lys er stærkere og mere afs
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Scientific American Content: Global
What Would You Ask an Astronaut on the Space Station? Ever wonder what children on the other side of the globe wonder about? I’m physics educator, with the Peace Corps' Let Girls Learn Program in Guinea, West Africa, and an introduction to our space unit, I asked my students to come up with questions to submit to Joe Accaba, a Returned Peace Corps Volunteer and astronaut who is currently orbiting earth in the International Space Station. My students
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Phys.org - latest science and technology news stories
Robots do chin-ups, pushups and situps for the sake of science The difference between previous humanoid prototypes, which use conventional design principles, and Kenshiro and Kengoro, which closely mimic human anatomy. Credit: Carla Schaffer / AAAS A team of Japanese engineers has designed robots that can perform pushups , do crunches, stretch and even sweat while doing so. The robots Kengoro and Kenshiro, described in the journal Science Robotics , can perf
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Scientific American Content: Global
To Find Life on Mars, Look Underground A popular strategy calls for investigating spots where waterborne sediment accumulated long ago, like the ancient lake-bed environment that NASA's Curiosity rover discovered inside Mars' 96-mile-wide (154 kilometers) Gale Crater. Here on Earth, such ancient habitats have preserved bountiful evidence of ancient life—but that doesn't mean the same will hold true on the Red Planet, according to
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Feed: All Latest
Crispr Isn’t Enough Any More. Get Ready for Gene Editing 2.0 In fewer than five years, the gene-editing technology known as Crispr has revolutionized the face and pace of modern biology. Since its ability to find, remove, and replace genetic material was first reported in 2012, scientists have published more than 5,000 papers mentioning Crispr. Biomedical researchers are embracing it to create better models of disease. And countless companies have spun up
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Latest Headlines | Science News
Here’s what you might have missed in space this year Missions to Jupiter and Saturn made big headlines this year, offering closeup views of the two gas giants. 2017 had plenty of other updates from exciting missions of years past. Juno The Juno spacecraft has kept a watchful eye on Jupiter since entering the gas giant’s orbit in 2016 . This year, Juno had seven planned science flybys of the planet, giving researchers a first intimate look at the Gr
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Phys.org - latest science and technology news stories
Facebook admits social media can be bad if you use it in this way Facebook's mission is to "bring the world closer together," but the tech firm this year has faced mounting criticism that social media could be ripping society apart. Last week, the social media giant acknowledged that spending time on its website can be bad for you—if you're merely consuming information, but not interacting with your family and friends. "Just like in person, interacting with p
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Scientific American Content: Global
Stinkhorns, Truffles, Smuts: The Amazing Diversity--and Possible Decline--of Mushrooms and Other Fungi The following essay is reprinted with permission from The Conversation , an online publication covering the latest research. “Whatever dressing one gives to mushrooms…they are not really good but to be sent back to the dungheap where they are born.” French philosopher Denis Diderot thus dismissed mushrooms in 1751 in his “ Encyclopedie .” Today his words would be dismissed in France,
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Phys.org - latest science and technology news stories
Social interactions override genetics when birds learn new songs Bengalese finches. Credit: Brainard lab / UCSF New UC San Francisco research finds that although young male songbirds are genetically predisposed to sound like their fathers, enriched early experience with a foster-father can overcome this genetic destiny. This finding has striking implications for our thinking about how experience influences the genetics of complex human traits like learning abi
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Phys.org - latest science and technology news stories
Puget Sound whales get a break from boaters at no loss to whale-watching Restrictions on vessel traffic have helped keep more boaters farther from critically endangered southern-resident killer whales, while not harming the whale-watch industry, a new study has found. Federal restrictions enacted in 2011 require whale-watch boats and other vessels to stay at least 200 yards away from whales. That's doubled the buffer. Yet whale-watch tourism continues to grow, the Nat
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Scientific American Content: Global
How Many Gigs Are You Wearing? The classic nightmare of suddenly realizing you’re naked in public could soon get a futuristic twist: it might involve the horror of losing not just your modesty but also your pass codes. Scientists recently created magnetic garments that they say can store data, automatically unlock doors or control a nearby smartphone with gestures. The concept of interactive “smart clothing” has drawn atte
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Phys.org - latest science and technology news stories
An ancient mastodon ignited a debate over humans' arrival in North America "Oh my God," Richard Cerutti said to himself. He bent down to pick up a sharp, splintered bone fragment. Its thickness and weight told him that it belonged to an animal, a very big animal. His mind started to race. He was standing at the foot of a slope being groomed by the California Department of Transportation for a road-widening project through the Sweetwater Valley near National City. Earthm
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Science : NPR
What Does A Newly Born Pacific Island Say About Life On Mars? Science can just knock to me the floor. Sometimes it's the revelation of some previously unseen phenomena. Other times, it's a new way to see something you thought you already understood. Then there are the times when connections pop up between things you never imagined to be connected. And sometimes, it's all of them at once. As a case in point, I give you this five-minute video explaining how t
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Phys.org - latest science and technology news stories
Alaskan microgrids offer energy resilience and independence Wind turbines supply renewable energy to microgrids across Alaska. Credit: Chris Pike, the Alaska Center for Energy and Power, University of Alaska Fairbanks The electrical grid in the contiguous United States is a behemoth of interconnected systems. If one section fails or is sabotaged, millions of citizens could be without power. Remote villages in Alaska provide an example of how safeguards co
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Science : NPR
North Korea Designed A Nuke. So Did This Truck Driver John Coster-Mullen has reverse-engineered America's first nuclear weapons and has self-published a book on his findings. Meredith Rizzo/NPR hide caption toggle caption Meredith Rizzo/NPR John Coster-Mullen has reverse-engineered America's first nuclear weapons and has self-published a book on his findings. Meredith Rizzo/NPR This year, deep inside a mountain, North Korea detonated a giant nuclear
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Viden
Fem "smarte" smuttere fra 2017 2017 har været fyldt med vigtige og imponerende teknologiske udviklinger inden for fx kunstig intelligens, selvkørende biler og rumfart. Og så er der alle de teknologiske dimser som under påskud af at være innovative forsøger at få os til at punge ud for endnu en ting, der vil havne i skuffen ved siden af alle de andre. Særligt den Smart alting -tendens, der dækker over ganske almindelige produkt
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Ingeniøren
Her er forbrændingsmotorens historie 1790-1860: En lang række forskere og ingeniører udvikler forskellige versioner af motorer baseret på princippet med en cylinder, hvori der foregår en forbrænding. I 1807 udvikler de franske brødre Claude og Nicéphore Niépce en motor, som forbrænder en blanding af kulstøv og harpiks. (Foto: INPI Archives) 1860: Belgieren Jean Joseph Etienne Lenoir bygger en stempelmotor, som drives af gas. Dette e
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Ingeniøren
Podcast-special: Synger forbrændingsmotoren på sidste vers? Transformator Ingeniørens fredagspodcast sætter strøm til ugens største nyheder inden for teknologi, forskning og naturvidenskab og analyserer de svingninger, der på godt og ondt transformerer verden og vores samfund. Anders Høeg Nissen er vært på Transformator Foto: PodLAB Abonnér på Transformator: Følg i iTunes På mobilen: Søg på Ingeniøren i din podcast-app. På iPhone er podcast-appen indbygge
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NYT > Science
ScienceTake: How It Works: The Large Mouth of the Largemouth Bass I talked with Dr. Olsen about the research. Our conversation has been condensed and edited for space and clarity. What is your research about? I study the evolution of motion in vertebrates. Why largemouth bass? They’re easy to get, and bass are powerful suction feeders, which was of interest to Ariel and Elizabeth. And there’s been a lot of work previously on largemouth bass. How do you get such
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NYT > Science
How Largemouth Bass Suck In Their Prey See how monkeys teach manners, elephants show empathy and ants imitate water in ScienceTake, combining cutting-edge research from the world of science with stunning footage of the natural world in action.
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Science-Based Medicine
A Misguided Study to Test the Reliability of Traditional Chinese Medicine Pulse Diagnosis In traditional Chinese medicine (TCM), palpation of the pulse at the wrist and inspection of the tongue are used to evaluate the patient’s state of health and make diagnoses. Are these actually useful diagnostic procedures? Pulse diagnosis History of pulse diagnosis Pulse diagnosis was an important part of ancient medicine in Egypt, Greece, India, Tibet, and elsewhere. The specific methods used w
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NYT > Science
Scientists Are Designing Artisanal Proteins for Your Body Now, it looks as if he and his colleagues have cracked it. Thanks in part to crowdsourced computers and smartphones belonging to over a million volunteers, the scientists have figured out how to choose the building blocks required to create a protein that will take on the shape they want. In a series of papers published this year, Dr. Baker and his colleagues unveiled the results of this work. Th
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EurekAlert! - Breaking News
Alaskan microgrids offer energy resilience and independence IMAGE: Wind turbines supply renewable energy to microgrids across Alaska. view more Credit: Chris Pike, the Alaska Center for Energy and Power, University of Alaska Fairbanks WASHINGTON, D.C., December 26, 2017 -- The electrical grid in the contiguous United States is a behemoth of interconnected systems. If one section fails or is sabotaged, millions of citizens could be without power. Remot
18h
Phys.org - latest science and technology news stories
Winds of worry: US fishermen fear forests of power turbines In this Monday, Aug. 15, 2016, file photo three wind turbines from the Deepwater Wind project stand in the Atlantic Ocean off Block Island, R.I. Fishermen are turning a wary eye toward an emerging upstart: the offshore wind industry. New Bedford, Mass., fishermen say they're concerned about navigating a forest of turbines to get to their historical fishing grounds and getting trawling gear caught
23h
Phys.org - latest science and technology news stories
Electric bike crackdown spurs delivery worker concern In this Thursday, Dec. 21, 2017 photo, a man making deliveries rides an electronic bike in New York. A plan to intensify a crackdown on electric bicycles is causing concern among the New York City's delivery workforce. (AP Photo/Seth Wenig) Cheap, electric bicycles have made life a lot easier for New York City's legions of restaurant delivery workers, but the party may be over in the New Year. Ci
23h

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