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Feed: All Latest
Waymo v. Uber, Tesla Struggles, and More Car News This WeekPlus: Why lidar's such a big deal, a robocar gets slapped, and Porsche ramps up its electric plans.
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Dagens Medicin
Minister: Bekymrende mange kræftpatienter fravælger behandlingsgarantiSundhedsminister Ellen Trane Nørby forlænger indberetningspligten for lunge- og pancreaskræft efter at et stort antal kræftpatienter har valgt at takke nej til at blive opereret til tiden på et andet sygehus end det, der ligger tættest på.
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Big Think
Why is there no map of the Bermuda Triangle? The U.S. Coast Guard has the answerThe Bermuda Triangle, one of the most mysterious places on Earth, doesn't have an official map and the U.S. Coast Guard is why. Read More
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EurekAlert! - Breaking News
Small gold mines in Senegal create high mercury contaminationA Duke-led study has found high levels of mercury and methylmercury in soils, sediments and rivers near artisanal gold mines in Senegal. Nearly every sample collected from four mining villages contained mercury levels at least ten times higher than World Health Organization and U.S. Environmental Protection Agency standards.
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EurekAlert! - Breaking News
Texas flood: Researchers compare pollution levels before and after Hurricane HarveyRecent years have seen rising interest in improving post-disaster research, with calls for more and better studies coming from the academic community and agencies such as the National Institutes of Health. Although understanding the wide-ranging effects of disasters is vital for an effective public health response, a lack of baseline data has made it difficult to attribute post-disaster changes in
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Phys.org - latest science and technology news stories
Five active volcanoes on my Asia Pacific 'Ring of Fire' watch-list right nowIn Indonesia, more than 197 million people live within 100km of a volcano, including more than 8.6 million inside a 10km radius.
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Phys.org - latest science and technology news stories
UPS, FedEx fall on report Amazon readying delivery serviceShares of FedEx and UPS slipped following a media report that Amazon.com is readying its own air delivery service, meaning not only that the companies may see diminished business from a massive client, but that they might have to compete against it.
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The Scientist RSS
All PLOS Submissions to Appear on bioRxivPapers sent to PLOS journals will be automatically uploaded to the preprint server before acceptance.
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The Scientist RSS
Image of the Day: Mantis GlassesResearchers outfitted praying mantises with miniature spectacles to investigate how they see the world.
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Dagens Medicin
Lovforslag om genomcenter får bred opbakningDet længe ventede og meget omtalte lovforslag om genomcenteret er i dag fremsat af sundhedsministeren. Dialogen om lovforslaget har bidraget til præciseringer og gjort det bedre.
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Phys.org - latest science and technology news stories
Considering the impact of the indoor chemistry cocktailA pair of researchers, one with the Chinese Academy of Sciences in China, the other with the University of Toronto in Canada has revisited the topic of indoor chemistry and its impact on human health. In their Perspective piece published in the journal Science, Sasho Gligorovski and Jonathan Abbatt suggest that more research should be done to determine what chemical reactions are occurring in home
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Live Science
Asteroid Skimming Past Earth Today May Loom Larger Than Exploding Russian MeteorAn asteroid that will fly safely past Earth today (Feb. 9) may be larger than the Chelyabinsk meteor that exploded over Russia five years ago. The newly found interloper, called 2018 CB, is estimated to be from 50 to 130 feet (15 to 40 meters) wide.
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Futurity.org
Abstract thinking makes robots better plannersResearchers have developed a method for helping robots plan for multi-step tasks by constructing abstract representations of the world around them. Their study is a step toward building robots that can think and act more like people. Planning is a monumentally difficult thing for robots, largely because of how they perceive and interact with the world. A robot’s perception of the world consists o
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Feed: All Latest
Esports Zerg-Rush the Olympics—But Can They Ever Become Official Events?An Olympic-affiliated tournament. Gamers carrying the torch. Are these real progress for esports, or just feints?
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Feed: All Latest
Winter Olympics 2018: Inside the Opening Ceremonies Drone ShowIntel Olympics ShowThe Pyeongchang opening ceremonies included a performance by 1,218 drones working in concert—a new world record.
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Feed: All Latest
Winter Olympics 2018: The Science of Ski WaxAthletes rely on secret chemicals and technicians to make skis both glide and grip.
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Science | The Guardian
Lab notes: Cheddar Man and Falcon X – not a crimefighting duo, but this week in science!Where to even begin this week? Could it be with the news that human eggs have been developed in the lab for the first time ? Or that researchers think they may have spotted a link between asparagine – a compound found in asparagus and other foods – and the spread of breast cancer ? Maybe that archaeologists have discovered an exciting new Neolithic monument in Windsor ? All of those things are ce
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The Atlantic
The ConversationConservatism Without Bigotry In December, Peter Beinart argued that conservatives would be more likely to reckon with their policies’ discriminatory effects if liberals stopped carelessly crying racist. Peter Beinart, in leaning over backwards to be evenhanded to conservatives and liberals, poses the wrong question. Before the election of Donald Trump, few liberals believed that all Republicans w
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Latest Headlines | Science News
Let your kids help you, and other parenting tips from traditional societiesHunter-gatherers and villagers have some parenting tips for modern moms and dads.
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Popular Science
The strange history of the Olympic Torch—and why it has to stay litEntertainment It’s hard to keep a fire burning across a many-thousand-mile relay race. The symbolic torch has come a long way since it began as Nazi propaganda, and every year it proves to be a new engineering challenge.
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Dagens Medicin
Hospitalerne skal nu administrere industri-betalt efteruddannelseFremover skal det være ledelsen på hospitalerne, der skal modtage og fordele pengene til læger og sygeplejerskes efteruddannelse fra industrien. Det har Danske Regioners bestyrelse vedtaget med nye retningslinjer.
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Phys.org - latest science and technology news stories
Efficient technique for isolating embryonic stem cells in cowsFor more than 35 years, scientists have tried to isolate embryonic stem cells in cows without much success. Under the right conditions, embryonic stem cells can grow indefinitely and make any other cell type or tissue, which has huge implications for creating genetically superior cows.
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Science : NPR
New Technology Aims To Take The Sugar Out Of Gelato — Not The FlavorThe Italian treat requires a certain formula to make it just right, and that means sugar. But as more people try to eat healthy, gelaterias must keep pace. A new machine is a step in that direction. (Image credit: Irina Marwan/Getty Images)
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Science-Based Medicine
The 2018 Flu Epidemic: Hives and other Influenza Related NonsenseWhile it isn't likely to be the flumaggedon, it is shaping up to be a really bad flu season. Unfortunately there is a lot of overzealous news coverage that I fear is causing more anxiety among parents than is warranted.
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Phys.org - latest science and technology news stories
Will a cold winter kill off ticks?The bad news is that even particularly harsh winter weather – like that experienced by much of the East Coast this year – won't kill off ticks. They are hardy little critters. However, a brutal winter could still have an effect on tick populations. Maybe.
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Phys.org - latest science and technology news stories
3-D printable tools to study astronaut healthIf humans are destined for deep space, they need to understand the space environment changes health, including aging and antibiotic resistance.
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Phys.org - latest science and technology news stories
'Optically pumped' laser closer to improving processing speed of sensorsImagine creating a material for the digital information highway that allows a fast lane of laser light that zips data past the traditional silicon chips.
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Ingeniøren
Vinter-OL: VR bringer skadet skiløber i formAlpinskiløberen Laurene Ross har tilbragt mere tid med en mobiltelefon spændt ud for øjnene for at øge chancen for at komme til Sydkorea end reel tid på pisten med sne og skibrædder under fødderne.
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TED Talks Daily (SD video)
"My Fine Reward" | Tito DelerBlues musician Tito Deler combines the sounds of his New York upbringing with the style of pre-war Mississippi Delta blues. He takes the stage, singing and strumming a stirring rendition of his song, "My Fine Reward."
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The Scientist RSS
Canada Plans to Boost Basic Science SpendingThe federal budget, expected before the end of March, may substantially raise funding for research.
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Phys.org - latest science and technology news stories
Hayward fault earthquake simulations increase fidelity of ground motionsIn the next 30 years, there is a one-in-three chance that the Hayward fault will rupture with a 6.7 magnitude or higher earthquake, according to the United States Geologic Survey (USGS). Such an earthquake will cause widespread damage to structures, transportation and utilities, as well as economic and social disruption in the East Bay.
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Phys.org - latest science and technology news stories
New silicon chip for helping build quantum computers and securing our informationResearchers at the University of Bristol's Quantum Engineering Technology Labs have demonstrated a new type of silicon chip that can help building and testing quantum computers and could find their way into your mobile phone to secure information.
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Phys.org - latest science and technology news stories
Video: Dropping the bass in freefallOn 7 February 2018, 10 years to the day that Europe's Columbus space laboratory was launched to the International Space Station, 20 lucky clubbers got a taste of weightlessness – not to conduct gravity-free science but to party with superstar DJs Steve Aoki, W&W and Le Shuuk.
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Phys.org - latest science and technology news stories
Microscope combines confocal microspectroscopy and 3-D scanning probe nanotomographyResearchers at the National Research Nuclear University MEPhI (Russia) and international colleagues have proposed an original approach to nanoscale 3-D analysis of materials. Their results are published in Ultramicroscopy.
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Phys.org - latest science and technology news stories
Cockroaches build spatial maps of olfactory stimuli to track potential matesMale cockroaches can sense the spatial distribution of female pheromones to locate a mate, according to researchers from Hokkaido University and the University of Konstanz. Cockroaches are nocturnal and heavily rely on olfaction for finding food and mating partners in the dark. However, plumes emitted from an odor source are not smooth or continuous, and have no clear concentration gradient. They
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Phys.org - latest science and technology news stories
Chemical composition of aircraft exhaust aerosols investigatedCan aircraft pollutant emissions be reduced by using biofuels? And what influence does an alternative fuel have on the formation of contrails? In mid-January, a joint German Aerospace Center (DLR) and US space agency NASA research project, with the participation of the Max Planck Institute for Chemistry and the Institute for Atmospheric Physics (IPA) of the Johannes Gutenberg University (JGU) in M
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The Atlantic
The 15:17 to Paris Is a Bizarre Re-creation of Real-Life BraveryParis Clint EastwoodI’m here to report what seems like a serious inaccuracy in the advertising of The 15:17 to Paris . According to the film’s poster, it was directed by Clint Eastwood, but I’m pretty sure the drama I watched was made by Tommy Wiseau—the eccentric artist behind the “so bad it’s good,” cult-classic movie The Room . How else to explain the halting dialogue, the way entire scenes have absolutely no bea
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Behind Artificial Intelligence Lurk Oddball Low-Paid TasksAs researchers attempt to apply artificial intelligence to daily life, they're paying "crowd actors" to film themselves performing routine tasks.
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Feed: All Latest
Facing Water Crisis, Cape Town Turns to DesalinationPockets of humanity may have to rely on desalination to survive drought in the very near future.
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Feed: All Latest
Polisis AI Reads Privacy Policies So You Don't Have ToPolisis, a machine-learning-trained tool, automatically produces readable charts of where your data ends up for any online service.
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Phys.org - latest science and technology news stories
A lightning-based nowcast-warning approach to predict short-duration rainfallPrevious studies have indicated a worldwide increasing trend of intense precipitation events under the influence of global warming. Heavy precipitation events increase the risk of flooding, exerting devastating effects on human society and the environment, especially for metropolises with dense populations. As one of the largest cities in the world, Beijing is highly vulnerable to increasingly fre
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Phys.org - latest science and technology news stories
Interference as a new method for cooling quantum devicesTheoretical physicists propose to use negative interference to control heat flow in quantum devices. Their study has been published in Physical Review Letters.
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Phys.org - latest science and technology news stories
Antibacterial applications of graphene oxidesBacterial infections are among the greatest threats to human health. However, due to the increasing spread of multidrug-resistant bacteria, the current antibiotic supply appears to be insufficient, thereby necessitating the exploration of novel antibacterial agents. Nano-antibacterial agents represent a new strategy for bacterial treatment. Compared with antibiotics, nano-antibacterial agents have
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Phys.org - latest science and technology news stories
Ultra-efficient removal of carbon monoxide using gold nanoparticles on a molecular supportResearchers from Tokyo Metropolitan University have developed a way to mount gold nanoparticles on a molecular support known as a polyoxometalate (POM). They successfully applied this to realize nearly 100 percent conversion of carbon monoxide (CO) over a wide temperature range, demonstrating stable performance over long periods of time. They showed how traces of water uniquely contribute to the c
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Phys.org - latest science and technology news stories
Britain's Mirror buys Express for £126.7m as sales dropThe publisher of Britain's left-wing Daily Mirror newspaper struck a £126.7 million deal on Friday to buy a series of titles including the right-wing Daily Express in a bid to stem a decline in advertising revenues and sales.
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Phys.org - latest science and technology news stories
Giant lava dome confirmed in Japan's Kikai CalderaSince the Kobe Ocean Bottom Exploration Center (KOBEC) was established in 2015, it has carried out three survey voyages to the Kikai Caldera, south of Japan's main islands. Based on these voyages, researchers have confirmed that a giant lava dome was created after the caldera-forming supereruption 7300 years ago. The dome is in the world's largest class of post-caldera volcano, with a volume of ov
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Phys.org - latest science and technology news stories
Scientists observe nanowires as they growAt DESY's X-ray source PETRA III, scientists have followed the growth of tiny wires of gallium arsenide live. Their observations reveal exact details of the growth process responsible for the evolving shape and crystal structure of the crystalline nanowires. The findings also provide new approaches to tailoring nanowires with desired properties for specific applications. The scientists, headed by
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Phys.org - latest science and technology news stories
First hybrid nanotech device mimicking blood-brain barrierResearchers at IIT-Istituto Italiano di Tecnologia fabricated an artificial device reproducing a 1:1 scale model of the blood-brain barrier (BBB), the anatomical and functional structure that protects the central nervous system from external toxins, but which also screens drugs when they are injected intravenously. The device, which is a combination of artificial and biological components, is fund
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Scientific American Content: Global
Why the Disease Definition of Addiction Does Far More Harm Than GoodAmong other problems, it has obstructed other channels of investigation, including the social, psychological and societal roots of addiction -- Read more on ScientificAmerican.com
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Science | The Guardian
'Britain is a sad, leaderless and confused place': your best comments todayWe look at some of the articles provoking reader conversation today, including the single market, space exploration and single-pilot planes The need for Britain to leave the EU but not the single market , an article on the revival of a “state embraced Nasa” and discussion on whether you would fly in a single-pilot jet have got you talking today. To join in the conversation you can click on the li
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Scientific American Content: Global
Go Figure: Why Olympic Ice Skaters Don't Fall Flat on Their FacesThe athletes’ brains get rewired with practice to counteract reflexes and execute complex routines -- Read more on ScientificAmerican.com
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Science | The Guardian
'He's one of us': modern neighbours welcome Cheddar ManDNA tests suggesting man who lived 10,000 years ago had dark skin and blue eyes cause a stir Rachel Andrews, who was tending the bar at the Black Dog Saloon, a wild west-themed cider pub at the foot of Cheddar Gorge, was not going to have a word said against the village’s most famous former resident. “We’re very proud of Cheddar Man,” she said. “There’s a really good, strong community spirit arou
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Nyheder - Forskning - Videnskab
Fødevareuddannelse flytter universitetKandidatuddannelsen i integrerede fødevarestudier vil fra den 1. september 2018 blive flyttet...
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Proceedings of the National Academy of Sciences current issue
No strong evidence that authoritarian attitudes are driven by a lack of control [Social Sciences]Kakkar and Sivanathan (1) provide new evidence of the link between economic crises and the preference for dominant leaders and strengthen previous evidence of the influence of economic crises on authoritarianism (2–5). However, the authors’ interpretation of why economic uncertainty favors dominant leaders entails two further predictions that are not...
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Proceedings of the National Academy of Sciences current issue
Reply to Safra et al.: Lack of theoretical rationale and selective analysis does not imply no strong evidence [Social Sciences]Safra et al. (1) contend that lack of control is not the mechanism for our findings (2); instead, distrust is a better candidate because of its greater explanatory power. There are several issues with their conjecture. First, study 1 was aimed at demonstrating the main effect of economic uncertainty on...
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Proceedings of the National Academy of Sciences current issue
Global models underestimate large decadal declining and rising water storage trends relative to GRACE satellite data [Environmental Sciences]Assessing reliability of global models is critical because of increasing reliance on these models to address past and projected future climate and human stresses on global water resources. Here, we evaluate model reliability based on a comprehensive comparison of decadal trends (2002–2014) in land water storage from seven global models...
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Proceedings of the National Academy of Sciences current issue
Shape-directed dynamics of active colloids powered by induced-charge electrophoresis [Physics]The symmetry and shape of colloidal particles can direct complex particle motions through fluid environments powered by simple energy inputs. The ability to rationally design or “program” the dynamics of such active colloids is an important step toward the realization of colloidal machines, in which components assemble spontaneously in space...
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Proceedings of the National Academy of Sciences current issue
Surface structure evolution in a homologous series of ionic liquids [Physics]Interfaces of room temperature ionic liquids (RTILs) are important for both applications and basic science and are therefore intensely studied. However, the evolution of their interface structure with the cation’s alkyl chain length n from Coulomb to van der Waals interaction domination has not yet been studied for even a...
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Proceedings of the National Academy of Sciences current issue
A neurochemical hypothesis for the origin of hominids [Anthropology]It has always been difficult to account for the evolution of certain human characters such as language, empathy, and altruism via individual reproductive success. However, the striatum, a subcortical region originally thought to be exclusively motor, is now known to contribute to social behaviors and “personality styles” that may link...
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Proceedings of the National Academy of Sciences current issue
Hsp90 chaperones hemoglobin maturation in erythroid and nonerythroid cells [Cell Biology]Maturation of adult (α2β2) and fetal hemoglobin (α2γ2) tetramers requires that heme be incorporated into each globin. While hemoglobin alpha (Hb-α) relies on a specific erythroid chaperone (alpha Hb-stabilizing protein, AHSP), the other chaperones that may help mature the partner globins (Hb-γ or Hb-β) in erythroid cells, or may enable...
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Proceedings of the National Academy of Sciences current issue
Extracellular vesicle budding is inhibited by redundant regulators of TAT-5 flippase localization and phospholipid asymmetry [Cell Biology]Cells release extracellular vesicles (EVs) that mediate intercellular communication and repair damaged membranes. Despite the pleiotropic functions of EVs in vitro, their in vivo function is debated, largely because it is unclear how to induce or inhibit their formation. In particular, the mechanisms of EV release by plasma membrane budding...
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Proceedings of the National Academy of Sciences current issue
Cytocapsular tubes conduct cell translocation [Cell Biology]Cell locomotion is essential for multicellular organism embryo development, organ homeostasis, tissue regeneration, immune responses, and tumor metastasis. Here we report that single mammalian cells can generate two extracellular membranous compartments: cytocapsulae and cytocapsular tubes. Cells migrate in cytocapsulae and engender cytocapsular tubes, which exhibit pleiotropic biological function
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Proceedings of the National Academy of Sciences current issue
Saa3 is a key mediator of the protumorigenic properties of cancer-associated fibroblasts in pancreatic tumors [Cell Biology]Pancreatic ductal adenocarcinoma (PDAC) is characterized by the presence of abundant desmoplastic stroma primarily composed of cancer-associated fibroblasts (CAFs). It is generally accepted that CAFs stimulate tumor progression and might be implicated in drug resistance and immunosuppression. Here, we have compared the transcriptional profile of PDGFRα+ CAFs isolated from genetically...
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Proceedings of the National Academy of Sciences current issue
Assembly and ecological function of the root microbiome across angiosperm plant species [Ecology]Across plants and animals, host-associated microbial communities play fundamental roles in host nutrition, development, and immunity. The factors that shape host–microbiome interactions are poorly understood, yet essential for understanding the evolution and ecology of these symbioses. Plant roots assemble two distinct microbial compartments from surrounding soil: the rhizosphere (microbes surroun
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Proceedings of the National Academy of Sciences current issue
Evolutionary history of carbon monoxide dehydrogenase/acetyl-CoA synthase, one of the oldest enzymatic complexes [Evolution]Carbon monoxide dehydrogenase/acetyl-CoA synthase (CODH/ACS) is a five-subunit enzyme complex responsible for the carbonyl branch of the Wood–Ljungdahl (WL) pathway, considered one of the most ancient metabolisms for anaerobic carbon fixation, but its origin and evolutionary history have been unclear. While traditionally associated with methanogens and acetogens, the presence of...
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Proceedings of the National Academy of Sciences current issue
Evolution of vertical and oblique transmission under fluctuating selection [Evolution]The evolution and maintenance of social learning, in competition with individual learning, under fluctuating selection have been well-studied in the theory of cultural evolution. Here, we study competition between vertical and oblique cultural transmission of a dichotomous phenotype under constant, periodically cycling, and randomly fluctuating selection. Conditions are derived for...
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Proceedings of the National Academy of Sciences current issue
Nonsense-mediated mRNA decay factors cure most [PSI+] prion variants [Genetics]The yeast prion [PSI+] is a self-propagating amyloid of Sup35p with a folded in-register parallel β-sheet architecture. In a genetic screen for antiprion genes, using the yeast knockout collection, UPF1/NAM7 and UPF3, encoding nonsense-mediated mRNA decay (NMD) factors, were frequently detected. Almost all [PSI+] variants arising in the absence of...
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Proceedings of the National Academy of Sciences current issue
IL-1{beta} enables CNS access to CCR2hi monocytes and the generation of pathogenic cells through GM-CSF released by CNS endothelial cells [Immunology and Inflammation]Molecular interventions that limit pathogenic CNS inflammation are used to treat autoimmune conditions such as multiple sclerosis (MS). Remarkably, IL-1β–knockout mice are highly resistant to experimental autoimmune encephalomyelitis (EAE), an animal model of MS. Here, we show that interfering with the IL-1β/IL-1R1 axis severely impairs the transmigration of myeloid cells...
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Proceedings of the National Academy of Sciences current issue
Differing roles of CD1d2 and CD1d1 proteins in type I natural killer T cell development and function [Immunology and Inflammation]MHC class I-like CD1 molecules have evolved to present lipid-based antigens to T cells. Differences in the antigen-binding clefts of the CD1 family members determine the conformation and size of the lipids that are presented, although the factors that shape CD1 diversity remain unclear. In mice, two homologous genes, CD1D1...
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Proceedings of the National Academy of Sciences current issue
Regulation of inflammatory responses by dynamic subcellular localization of RNA-binding protein Arid5a [Immunology and Inflammation]Adenine-thymine (AT)-rich interactive domain 5a (Arid5a) is an RNA-binding protein found in the cytoplasm and nucleus of normally growing cells. Although Arid5a is known to play an important role in immune regulation, whether and how Arid5a subcellular localization impacts immune regulation has remained unclear. In this study, we generated Arid5a...
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Proceedings of the National Academy of Sciences current issue
Establishment of the early cilia preassembly protein complex during motile ciliogenesis [Medical Sciences]Motile cilia are characterized by dynein motor units, which preassemble in the cytoplasm before trafficking into the cilia. Proteins required for dynein preassembly were discovered by finding human mutations that result in absent ciliary motors, but little is known about their expression, function, or interactions. By monitoring ciliogenesis in primary...
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Proceedings of the National Academy of Sciences current issue
MYCN-amplified neuroblastoma maintains an aggressive and undifferentiated phenotype by deregulation of estrogen and NGF signaling [Medical Sciences]Neuroblastoma (NB) is a remarkably heterogenic childhood tumor of the sympathetic nervous system with clinical behavior ranging from spontaneous regression to poorly differentiated tumors and metastasis. MYCN is amplified in 20% of cases and correlates with an undifferentiated, aggressive phenotype and poor prognosis. Estrogen receptor alpha (ERα) and the nerve...
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Proceedings of the National Academy of Sciences current issue
Chemotherapy induces enrichment of CD47+/CD73+/PDL1+ immune evasive triple-negative breast cancer cells [Medical Sciences]Triple-negative breast cancer (TNBC) is treated with cytotoxic chemotherapy and is often characterized by early relapse and metastasis. To form a secondary (recurrent and/or metastatic) tumor, a breast cancer cell must evade the innate and adaptive immune systems. CD47 enables cancer cells to evade killing by macrophages, whereas CD73 and...
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Proceedings of the National Academy of Sciences current issue
Increased thermogenesis by a noncanonical pathway in ANGPTL3/8-deficient mice [Medical Sciences]Dietary triglyceride (TG) is the most efficient energy substrate. It is processed and stored at substantially lower metabolic cost than is protein or carbohydrate. In fed animals, circulating TGs are preferentially routed for storage to white adipose tissue (WAT) by angiopoietin-like proteins 3 (A3) and 8 (A8). Here, we show...
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Proceedings of the National Academy of Sciences current issue
Structure and function of the archaeal response regulator CheY [Microbiology]Motility is a central feature of many microorganisms and provides an efficient strategy to respond to environmental changes. Bacteria and archaea have developed fundamentally different rotary motors enabling their motility, termed flagellum and archaellum, respectively. Bacterial motility along chemical gradients, called chemotaxis, critically relies on the response regulator CheY, which,...
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Proceedings of the National Academy of Sciences current issue
Sporadic on/off switching of HTLV-1 Tax expression is crucial to maintain the whole population of virus-induced leukemic cells [Microbiology]Viruses causing chronic infection artfully manipulate infected cells to enable viral persistence in vivo under the pressure of immunity. Human T-cell leukemia virus type 1 (HTLV-1) establishes persistent infection mainly in CD4+ T cells in vivo and induces leukemia in this subset. HTLV-1–encoded Tax is a critical transactivator of viral...
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Proceedings of the National Academy of Sciences current issue
Intracellular Ca2+ stores control in vivo neuronal hyperactivity in a mouse model of Alzheimer’s disease [Neuroscience]Neuronal hyperactivity is the emerging functional hallmark of Alzheimer’s disease (AD) in both humans and different mouse models, mediating an impairment of memory and cognition. The mechanisms underlying neuronal hyperactivity remain, however, elusive. In vivo Ca2+ imaging of somatic, dendritic, and axonal activity patterns of cortical neurons revealed that both...
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Proceedings of the National Academy of Sciences current issue
Tau induces blood vessel abnormalities and angiogenesis-related gene expression in P301L transgenic mice and human Alzheimer’s disease [Neuroscience]Mixed pathology, with both Alzheimer’s disease and vascular abnormalities, is the most common cause of clinical dementia in the elderly. While usually thought to be concurrent diseases, the fact that changes in cerebral blood flow are a prominent early and persistent alteration in Alzheimer’s disease raises the possibility that vascular...
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Proceedings of the National Academy of Sciences current issue
Focal versus distributed temporal cortex activity for speech sound category assignment [Neuroscience]Percepts and words can be decoded from distributed neural activity measures. However, the existence of widespread representations might conflict with the more classical notions of hierarchical processing and efficient coding, which are especially relevant in speech processing. Using fMRI and magnetoencephalography during syllable identification, we show that sensory and decisional...
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Proceedings of the National Academy of Sciences current issue
The eardrums move when the eyes move: A multisensory effect on the mechanics of hearing [Neuroscience]Interactions between sensory pathways such as the visual and auditory systems are known to occur in the brain, but where they first occur is uncertain. Here, we show a multimodal interaction evident at the eardrum. Ear canal microphone measurements in humans (n = 19 ears in 16 subjects) and monkeys...
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Proceedings of the National Academy of Sciences current issue
Involvement of Aryl hydrocarbon receptor in myelination and in human nerve sheath tumorigenesis [Neuroscience]Aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor involved in xenobiotic metabolism. Plexiform neurofibromas (PNFs) can transform into malignant peripheral nerve sheath tumors (MPNSTs) that are resistant to existing therapies. These tumors are primarily composed of Schwann cells. In addition to neurofibromatosis type 1 (NF1) gene inactivation, further genetic...
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Proceedings of the National Academy of Sciences current issue
Early hominids may have been weed species [Anthropology]Panid, gorillid, and hominid social structures appear to have diverged as dramatically as did their locomotor patterns as they emerged from a late Miocene last common ancestor (LCA). Despite their elimination of the sectorial canine complex and adoption of bipedality with its attendant removal of their ready access to the...
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Proceedings of the National Academy of Sciences current issue
Redirection of lipid flux toward phospholipids in yeast increases fatty acid turnover and secretion [Applied Biological Sciences]Bio-based production of fatty acids and fatty acid-derived products can enable sustainable substitution of petroleum-derived fuels and chemicals. However, developing new microbial cell factories for producing high levels of fatty acids requires extensive engineering of lipid metabolism, a complex and tightly regulated metabolic network. Here we generated a Saccharomyces cerevisiae...
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Proceedings of the National Academy of Sciences current issue
Structural flexibility and protein adaptation to temperature: Molecular dynamics analysis of malate dehydrogenases of marine molluscs [Biochemistry]Orthologous proteins of species adapted to different temperatures exhibit differences in stability and function that are interpreted to reflect adaptive variation in structural “flexibility.” However, quantifying flexibility and comparing flexibility across proteins has remained a challenge. To address this issue, we examined temperature effects on cytosolic malate dehydrogenase (cMDH) orthologs..
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Proceedings of the National Academy of Sciences current issue
Molecular clutch drives cell response to surface viscosity [Biophysics and Computational Biology]Cell response to matrix rigidity has been explained by the mechanical properties of the actin-talin-integrin-fibronectin clutch. Here the molecular clutch model is extended to account for cell interactions with purely viscous surfaces (i.e., without an elastic component). Supported lipid bilayers present an idealized and controllable system through which to study...
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Proceedings of the National Academy of Sciences current issue
Confirmation of intersubunit connectivity and topology of designed protein complexes by native MS [Biophysics and Computational Biology]Computational protein design provides the tools to expand the diversity of protein complexes beyond those found in nature. Understanding the rules that drive proteins to interact with each other enables the design of protein–protein interactions to generate specific protein assemblies. In this work, we designed protein–protein interfaces between dimers and...
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Proceedings of the National Academy of Sciences current issue
Modular origins of biological electron transfer chains [Biophysics and Computational Biology]Oxidoreductases catalyze electron transfer reactions that ultimately provide the energy for life. A limited set of ancestral protein-metal modules are presumably the building blocks that evolved into this diverse protein family. However, the identity of these modules and their path to modern oxidoreductases is unknown. Using a comparative structural analysis...
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Proceedings of the National Academy of Sciences current issue
Full molecular trajectories of RNA polymerase at single base-pair resolution [Biophysics and Computational Biology]In recent years, highly stable optical tweezers systems have enabled the characterization of the dynamics of molecular motors at very high resolution. However, the motion of many motors with angstrom-scale dynamics cannot be consistently resolved due to poor signal-to-noise ratio. Using an acousto-optic deflector to generate a “time-shared” dual-optical trap,...
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Proceedings of the National Academy of Sciences current issue
High-resolution cryo-EM structures of actin-bound myosin states reveal the mechanism of myosin force sensing [Biophysics and Computational Biology]Myosins adjust their power outputs in response to mechanical loads in an isoform-dependent manner, resulting in their ability to dynamically adapt to a range of motile challenges. Here, we reveal the structural basis for force-sensing based on near-atomic resolution structures of one rigor and two ADP-bound states of myosin-IB (myo1b)...
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Proceedings of the National Academy of Sciences current issue
Context-dependent functions of angiopoietin 2 are determined by the endothelial phosphatase VEPTP [Cell Biology]The angiopoietin (ANGPT)–TIE2/TEK signaling pathway is essential for blood and lymphatic vascular homeostasis. ANGPT1 is a potent TIE2 activator, whereas ANGPT2 functions as a context-dependent agonist/antagonist. In disease, ANGPT2-mediated inhibition of TIE2 in blood vessels is linked to vascular leak, inflammation, and metastasis. Using conditional knockout studies in mice, we...
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Proceedings of the National Academy of Sciences current issue
Fluorine-donating electrolytes enable highly reversible 5-V-class Li metal batteries [Chemistry]Lithium metal has gravimetric capacity ∼10× that of graphite which incentivizes rechargeable Li metal batteries (RLMB) development. A key factor that limits practical use of RLMB is morphological instability of Li metal anode upon electrodeposition, reflected by the uncontrolled area growth of solid–electrolyte interphase that traps cyclable Li, quantified by...
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Proceedings of the National Academy of Sciences current issue
Antibody detection by agglutination-PCR (ADAP) enables early diagnosis of HIV infection by oral fluid analysis [Chemistry]Oral fluid (OF) is a highly effective substrate for population-based HIV screening efforts, as it is noninfectious and significantly easier to collect than blood. However, anti-HIV antibodies are found at far lower concentrations in OF compared with blood, leading to poor sensitivity and a longer period of time from infection...
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Proceedings of the National Academy of Sciences current issue
Ocean convergence and the dispersion of flotsam [Earth, Atmospheric, and Planetary Sciences]Floating oil, plastics, and marine organisms are continually redistributed by ocean surface currents. Prediction of their resulting distribution on the surface is a fundamental, long-standing, and practically important problem. The dominant paradigm is dispersion within the dynamical context of a nondivergent flow: objects initially close together will on average spread...
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Proceedings of the National Academy of Sciences current issue
Precipitation formation from orographic cloud seeding [Earth, Atmospheric, and Planetary Sciences]Throughout the western United States and other semiarid mountainous regions across the globe, water supplies are fed primarily through the melting of snowpack. Growing populations place higher demands on water, while warmer winters and earlier springs reduce its supply. Water managers are tantalized by the prospect of cloud seeding as...
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Proceedings of the National Academy of Sciences current issue
Eocene greenhouse climate revealed by coupled clumped isotope-Mg/Ca thermometry [Earth, Atmospheric, and Planetary Sciences]Past greenhouse periods with elevated atmospheric CO2 were characterized by globally warmer sea-surface temperatures (SST). However, the extent to which the high latitudes warmed to a greater degree than the tropics (polar amplification) remains poorly constrained, in particular because there are only a few temperature reconstructions from the tropics. Consequently,...
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Proceedings of the National Academy of Sciences current issue
Potential for western US seasonal snowpack prediction [Earth, Atmospheric, and Planetary Sciences]Western US snowpack—snow that accumulates on the ground in the mountains—plays a critical role in regional hydroclimate and water supply, with 80% of snowmelt runoff being used for agriculture. While climate projections provide estimates of snowpack loss by the end of the century and weather forecasts provide predictions of weather...
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Proceedings of the National Academy of Sciences current issue
Urban flux measurements reveal a large pool of oxygenated volatile organic compound emissions [Earth, Atmospheric, and Planetary Sciences]Atmospheric chemistry is fueled by a large annual influx of nonmethane volatile organic compounds (NMVOC). These compounds influence ozone formation, lead to secondary organic aerosol production, and play a significant role for the oxidizing capacity of the atmosphere. The anthropogenic NMVOC budget is considerably uncertain due to the diversity of...
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Proceedings of the National Academy of Sciences current issue
Productivity, biodiversity, and pathogens influence the global hunter-gatherer population density [Ecology]The environmental drivers of species distributions and abundances are at the core of ecological research. However, the effects of these drivers on human abundance are not well-known. Here, we report how net primary productivity, biodiversity, and pathogen stress affect human population density using global ethnographic hunter-gatherer data. Our results show...
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Proceedings of the National Academy of Sciences current issue
Human ectoparasites and the spread of plague in Europe during the Second Pandemic [Ecology]Plague, caused by the bacterium Yersinia pestis, can spread through human populations by multiple transmission pathways. Today, most human plague cases are bubonic, caused by spillover of infected fleas from rodent epizootics, or pneumonic, caused by inhalation of infectious droplets. However, little is known about the historical spread of plague...
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Proceedings of the National Academy of Sciences current issue
Rotational 3D printing of damage-tolerant composites with programmable mechanics [Engineering]Natural composites exhibit exceptional mechanical performance that often arises from complex fiber arrangements within continuous matrices. Inspired by these natural systems, we developed a rotational 3D printing method that enables spatially controlled orientation of short fibers in polymer matrices solely by varying the nozzle rotation speed relative to the printing...
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Proceedings of the National Academy of Sciences current issue
Aberration-corrected cryoimmersion light microscopy [Engineering]Cryogenic fluorescent light microscopy of flash-frozen cells stands out by artifact-free fixation and very little photobleaching of the fluorophores used. To attain the highest level of resolution, aberration-free immersion objectives with accurately matched immersion media are required, but both do not exist for imaging below the glass-transition temperature of water....
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Proceedings of the National Academy of Sciences current issue
Engineered bio-inspired coating for passive flow control [Engineering]Flow separation and vortex shedding are some of the most common phenomena experienced by bluff bodies under relative motion with the surrounding medium. They often result in a recirculation bubble in regions with adverse pressure gradient, which typically reduces efficiency in vehicles and increases loading on structures. Here, the ability...
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Proceedings of the National Academy of Sciences current issue
Human bone perivascular niche-on-a-chip for studying metastatic colonization [Engineering]Eight out of 10 breast cancer patients die within 5 years after the primary tumor has spread to the bones. Tumor cells disseminated from the breast roam the vasculature, colonizing perivascular niches around blood capillaries. Slow flows support the niche maintenance by driving the oxygen, nutrients, and signaling factors from...
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Proceedings of the National Academy of Sciences current issue
Humidity determines snowpack ablation under a warming climate [Environmental Sciences]Climate change is altering historical patterns of snow accumulation and melt, threatening societal frameworks for water supply. However, decreases in spring snow water equivalent (SWE) and changes in snowmelt are not ubiquitous despite widespread warming in the western United States, highlighting the importance of latent and radiant energy fluxes in...
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Proceedings of the National Academy of Sciences current issue
Solution structure of sperm lysin yields novel insights into molecular dynamics of rapid protein evolution [Evolution]Protein evolution is driven by the sum of different physiochemical and genetic processes that usually results in strong purifying selection to maintain biochemical functions. However, proteins that are part of systems under arms race dynamics often evolve at unparalleled rates that can produce atypical biochemical properties. In the marine mollusk...
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Proceedings of the National Academy of Sciences current issue
BARD1 is necessary for ubiquitylation of nucleosomal histone H2A and for transcriptional regulation of estrogen metabolism genes [Genetics]Missense mutations that disrupt the RING domain of the tumor suppressor gene BRCA1 lead to increased risk of breast and ovarian cancer. The BRCA1 RING domain is a ubiquitin ligase, whose structure and function rely critically on forming a heterodimer with BARD1, which also harbors a RING domain. The function...
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Proceedings of the National Academy of Sciences current issue
Prediction of inherited genomic susceptibility to 20 common cancer types by a supervised machine-learning method [Genetics]Prevention and early intervention are the most effective ways of avoiding or minimizing psychological, physical, and financial suffering from cancer. However, such proactive action requires the ability to predict the individual’s susceptibility to cancer with a measure of probability. Of the triad of cancer-causing factors (inherited genomic susceptibility, environmental factors,...
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Proceedings of the National Academy of Sciences current issue
Genetic and epigenetic alterations in normal tissues have differential impacts on cancer risk among tissues [Genetics]Genetic and epigenetic alterations are both involved in carcinogenesis, and their low-level accumulation in normal tissues constitutes cancer risk. However, their relative importance has never been examined, as measurement of low-level mutations has been difficult. Here, we measured low-level accumulations of genetic and epigenetic alterations in normal tissues with low,...
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Proceedings of the National Academy of Sciences current issue
Nonfollicular reactivation of bone marrow resident memory CD4 T cells in immune clusters of the bone marrow [Immunology and Inflammation]The bone marrow maintains memory CD4 T cells, which provide memory to systemic antigens. Here we demonstrate that memory CD4 T cells are reactivated by antigen in the bone marrow. In a secondary immune response, antigen-specific T cells of the bone marrow mobilize and aggregate in immune clusters together with...
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Proceedings of the National Academy of Sciences current issue
Methyltransferases of gentamicin biosynthesis [Microbiology]Gentamicin C complex from Micromonospora echinospora remains a globally important antibiotic, and there is revived interest in the semisynthesis of analogs that might show improved therapeutic properties. The complex consists of five components differing in their methylation pattern at one or more sites in the molecule. We show here, using...
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Proceedings of the National Academy of Sciences current issue
Transcription factor Pebbled/RREB1 regulates injury-induced axon degeneration [Neuroscience]Genetic studies of Wallerian degeneration have led to the identification of signaling molecules (e.g., dSarm/Sarm1, Axundead, and Highwire) that function locally in axons to drive degeneration. Here we identify a role for the Drosophila C2H2 zinc finger transcription factor Pebbled [Peb, Ras-responsive element binding protein 1 (RREB1) in mammals] in...
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Proceedings of the National Academy of Sciences current issue
Transient visual pathway critical for normal development of primate grasping behavior [Neuroscience]An evolutionary hallmark of anthropoid primates, including humans, is the use of vision to guide precise manual movements. These behaviors are reliant on a specialized visual input to the posterior parietal cortex. Here, we show that normal primate reaching-and-grasping behavior depends critically on a visual pathway through the thalamic pulvinar,...
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Proceedings of the National Academy of Sciences current issue
Active learning machine learns to create new quantum experiments [Physics]How useful can machine learning be in a quantum laboratory? Here we raise the question of the potential of intelligent machines in the context of scientific research. A major motivation for the present work is the unknown reachability of various entanglement classes in quantum experiments. We investigate this question by...
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Proceedings of the National Academy of Sciences current issue
Abrupt change of the superconducting gap structure at the nematic critical point in FeSe1-xSx [Physics]The emergence of the nematic electronic state that breaks rotational symmetry is one of the most fascinating properties of the iron-based superconductors, and has relevance to cuprates as well. FeSe has a unique ground state in which superconductivity coexists with a nematic order without long-range magnetic ordering, providing a significant...
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Proceedings of the National Academy of Sciences current issue
Motile cilia of human airway epithelia contain hedgehog signaling components that mediate noncanonical hedgehog signaling [Physiology]Differentiated airway epithelia produce sonic hedgehog (SHH), which is found in the thin layer of liquid covering the airway surface. Although previous studies showed that vertebrate HH signaling requires primary cilia, as airway epithelia mature, the cells lose primary cilia and produce hundreds of motile cilia. Thus, whether airway epithelia...
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Proceedings of the National Academy of Sciences current issue
STAC proteins associate to the IQ domain of CaV1.2 and inhibit calcium-dependent inactivation [Physiology]The adaptor proteins STAC1, STAC2, and STAC3 represent a newly identified family of regulators of voltage-gated calcium channel (CaV) trafficking and function. The skeletal muscle isoform STAC3 is essential for excitation–contraction coupling and its mutation causes severe muscle disease. Recently, two distinct molecular domains in STAC3 were identified, necessary for...
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Proceedings of the National Academy of Sciences current issue
Nitrate modulates stem cell dynamics in Arabidopsis shoot meristems through cytokinins [Plant Biology]The shoot apical meristem (SAM) is responsible for the generation of all the aerial parts of plants. Given its critical role, dynamical changes in SAM activity should play a central role in the adaptation of plant architecture to the environment. Using quantitative microscopy, grafting experiments, and genetic perturbations, we connect...
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Proceedings of the National Academy of Sciences current issue
A virus-targeted plant receptor-like kinase promotes cell-to-cell spread of RNAi [Plant Biology]RNA interference (RNAi) in plants can move from cell to cell, allowing for systemic spread of an antiviral immune response. How this cell-to-cell spread of silencing is regulated is currently unknown. Here, we describe that the C4 protein from Tomato yellow leaf curl virus can inhibit the intercellular spread of...
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Proceedings of the National Academy of Sciences current issue
Tactile distance illusions reflect a coherent stretch of tactile space [Psychological and Cognitive Sciences]Illusions of the perception of distance between two touches on the skin have been described since the classic work of Weber in the 19th century. The perceptual mechanisms underlying such spatial distortions, however, remain poorly understood. One potential interpretation is that the representational space of touch is related to the...
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Proceedings of the National Academy of Sciences current issue
Frequency modulation of neural oscillations according to visual task demands [Psychological and Cognitive Sciences]Temporal integration in visual perception is thought to occur within cycles of occipital alpha-band (8–12 Hz) oscillations. Successive stimuli may be integrated when they fall within the same alpha cycle and segregated for different alpha cycles. Consequently, the speed of alpha oscillations correlates with the temporal resolution of perception, such...
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Proceedings of the National Academy of Sciences current issue
Basal forebrain contributes to default mode network regulation [Psychological and Cognitive Sciences]The default mode network (DMN) is a collection of cortical brain regions that is active during states of rest or quiet wakefulness in humans and other mammalian species. A pertinent characteristic of the DMN is a suppression of local field potential gamma activity during cognitive task performance as well as...
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Proceedings of the National Academy of Sciences current issue
Correction for Noh et al., ATRX tolerates activity-dependent histone H3 methyl/phos switching to maintain repetitive element silencing in neurons [Correction]COLLOQUIUM Correction for “ATRX tolerates activity-dependent histone H3 methyl/phos switching to maintain repetitive element silencing in neurons,” by Kyung-Min Noh, Ian Maze, Dan Zhao, Bin Xiang, Wendy Wenderski, Peter W. Lewis, Li Shen, Haitao Li, and C. David Allis, which was first published December 23, 2014; 10.1073/pnas.1411258112 (Proc Natl Acad...
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Proceedings of the National Academy of Sciences current issue
Correction for Ferrari et al., Hypoxia treatment reverses neurodegenerative disease in a mouse model of Leigh syndrome [Correction]MEDICAL SCIENCES Correction for “Hypoxia treatment reverses neurodegenerative disease in a mouse model of Leigh syndrome,” by Michele Ferrari, Isha H. Jain, Olga Goldberger, Emanuele Rezoagli, Robrecht Thoonen, Kai-Hung Chen, David E. Sosnovik, Marielle Scherrer-Crosbie, Vamsi K. Mootha, and Warren M. Zapol, which was first published May 8, 2017; 10.1073/pnas.1621511114...
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Proceedings of the National Academy of Sciences current issue
In This Issue [This Week in PNAS]Role of human fleas and body lice in Europe’s Black Death Y. pestis. Image courtesy of Flickr/National Institutes of Allergy and Infectious Diseases, NIH. Plague can be caused by the inhalation of aerosolized forms of the bacterium Yersinia pestis (pneumonic plague) or by the bite of rodent-borne fleas infected with...
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Proceedings of the National Academy of Sciences current issue
QnAs with Frank S. Bates [QnAs]Liquids are in an intriguing state of matter. They have the same approximate density of solids, yet lack any semblance of order and symmetry, both of which are the hallmarks of crystalline solids. Frank S. Bates of the University of Minnesota studies the in-between phases of matter that defy neat...
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Proceedings of the National Academy of Sciences current issue
Hunter-gatherer populations inform modern ecology [Anthropology]Our species Homo sapiens is extraordinarily successful, yet we are still subject to the same environmental constraints, such as famine and disease, as all other organisms (1). Fundamental approaches from ecology and evolution have proven useful for understanding how interactions with biotic (other species) and abiotic (physical) surroundings influence humanity’s...
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Proceedings of the National Academy of Sciences current issue
Pebbled makes ripples: A transcription factor primes glutamatergic but not cholinergic neurons for degeneration [Neuroscience]Neurons can extend axons that cover long distances, from several microns and up to 1 m in adult humans. Axon degeneration is a hallmark of several neurodegenerative diseases, such as amyotrophic lateral sclerosis, Huntington’s disease, Parkinson’s disease, and many more (1). Understanding the mechanisms maintaining axon integrity—and thus neuronal function—is...
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Proceedings of the National Academy of Sciences current issue
Ephemeral connections for reaching and grasping [Neuroscience]Bonsai is a tree-cultivation technique that has a rich history, spanning thousands of years. The goal is to grow an aesthetically pleasing miniature tree in a pot environment. One problem faced by practitioners of this art form is that the taller branches that grow first tend to extend outwards, shading...
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Proceedings of the National Academy of Sciences current issue
Transit-time and age distributions for nonlinear time-dependent compartmental systems [Ecology]Many processes in nature are modeled using compartmental systems (reservoir/pool/box systems). Usually, they are expressed as a set of first-order differential equations describing the transfer of matter across a network of compartments. The concepts of age of matter in compartments and the time required for particles to transit the system...
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Proceedings of the National Academy of Sciences current issue
Opinion: Valuation, liquidity price, and stability of cryptocurrencies [Economic Sciences]The spectacular rise of Bitcoin's price has attracted the attention of many, including government regulators and speculators and those who wish to use a virtual currency, often with little trace or record (1). On October 13, 2017, Bitcoin's market capitalization (the number of Bitcoins multiplied by the trading price) surpassed...
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Ingeniøren
Her er programmerne, hackerne elsker, du brugerEksperter fra Kaspersky og Triop laver en kort liste af programmer, du skal passe på med at bruge.
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Science current issue
Chemistry assessments go 3D
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Science current issue
Monocytes may shed light on melanoma therapy
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Science current issue
Synergistic approach to localized delivery
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Science current issue
Morphology, muscle capacity, skill, and maneuvering ability in hummingbirdsHow does agility evolve? This question is challenging because natural movement has many degrees of freedom and can be influenced by multiple traits. We used computer vision to record thousands of translations, rotations, and turns from more than 200 hummingbirds from 25 species, revealing that distinct performance metrics are correlated and that species diverge in their maneuvering style. Our ana
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Science current issue
Live imaging of neurogenesis in the adult mouse hippocampusNeural stem and progenitor cells (NSPCs) generate neurons throughout life in the mammalian hippocampus. We used chronic in vivo imaging and followed genetically labeled individual NSPCs and their progeny in the mouse hippocampus for up to 2 months. We show that NSPCs targeted by the endogenous Achaete-scute homolog 1 (Ascl1) promoter undergo limited rounds of symmetric and asymmetric divisions, e
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Science current issue
Coherent single-atom superradianceSuperradiance is a quantum phenomenon emerging in macroscopic systems whereby correlated single atoms cooperatively emit photons. Demonstration of controlled collective atom-field interactions has resulted from the ability to directly imprint correlations with an atomic ensemble. Here we report cavity-mediated coherent single-atom superradiance: Single atoms with predefined correlation traverse a
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Science current issue
A topological quantum optics interfaceThe application of topology in optics has led to a new paradigm in developing photonic devices with robust properties against disorder. Although considerable progress on topological phenomena has been achieved in the classical domain, the realization of strong light-matter coupling in the quantum domain remains unexplored. We demonstrate a strong interface between single quantum emitters and topo
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Science current issue
Building superlattices from individual nanoparticles via template-confined DNA-mediated assemblyDNA programmable assembly has been combined with top-down lithography to construct superlattices of discrete, reconfigurable nanoparticle architectures on a gold surface over large areas. Specifically, the assembly of individual colloidal plasmonic nanoparticles with different shapes and sizes is controlled by oligonucleotides containing "locked" nucleic acids and confined environments provided b
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Science current issue
Light amplification by seeded Kerr instabilityAmplification of femtosecond laser pulses typically requires a lasing medium or a nonlinear crystal. In either case, the chemical properties of the lasing medium or the momentum conservation in the nonlinear crystal constrain the frequency and the bandwidth of the amplified pulses. We demonstrate high gain amplification (greater than 1000) of widely tunable (0.5 to 2.2 micrometers) and short (les
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Science current issue
Atomic-resolution transmission electron microscopy of electron beam-sensitive crystalline materialsHigh-resolution imaging of electron beam–sensitive materials is one of the most difficult applications of transmission electron microscopy (TEM). The challenges are manifold, including the acquisition of images with extremely low beam doses, the time-constrained search for crystal zone axes, the precise image alignment, and the accurate determination of the defocus value. We develop a suite of me
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Science current issue
Near-infrared deep brain stimulation via upconversion nanoparticle-mediated optogeneticsOptogenetics has revolutionized the experimental interrogation of neural circuits and holds promise for the treatment of neurological disorders. It is limited, however, because visible light cannot penetrate deep inside brain tissue. Upconversion nanoparticles (UCNPs) absorb tissue-penetrating near-infrared (NIR) light and emit wavelength-specific visible light. Here, we demonstrate that molecula
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Science current issue
Defective cholesterol clearance limits remyelination in the aged central nervous systemAge-associated decline in regeneration capacity limits the restoration of nervous system functionality after injury. In a model for demyelination, we found that old mice fail to resolve the inflammatory response initiated after myelin damage. Aged phagocytes accumulated excessive amounts of myelin debris, which triggered cholesterol crystal formation and phagolysosomal membrane rupture and stimul
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Science current issue
Defining the physiological role of SRP in protein-targeting efficiency and specificityThe signal recognition particle (SRP) enables cotranslational delivery of proteins for translocation into the endoplasmic reticulum (ER), but its full in vivo role remains incompletely explored. We combined rapid auxin-induced SRP degradation with proximity-specific ribosome profiling to define SRP’s in vivo function in yeast. Despite the classic view that SRP recognizes amino-terminal signal seq
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Science current issue
Shared molecular neuropathology across major psychiatric disorders parallels polygenic overlapThe predisposition to neuropsychiatric disease involves a complex, polygenic, and pleiotropic genetic architecture. However, little is known about how genetic variants impart brain dysfunction or pathology. We used transcriptomic profiling as a quantitative readout of molecular brain-based phenotypes across five major psychiatric disorders—autism, schizophrenia, bipolar disorder, depression, and
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Science current issue
Atomic structures of low-complexity protein segments reveal kinked {beta} sheets that assemble networksSubcellular membraneless assemblies are a reinvigorated area of study in biology, with spirited scientific discussions on the forces between the low-complexity protein domains within these assemblies. To illuminate these forces, we determined the atomic structures of five segments from protein low-complexity domains associated with membraneless assemblies. Their common structural feature is the s
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Science current issue
New Products
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Science current issue
My climate change crisis
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Science current issue
Programming gene and engineered-cell therapies with synthetic biologyGene and engineered-cell therapies promise to treat diseases by genetically modifying cells to carry out therapeutic tasks. Although the field has had some success in treating monogenic disorders and hematological malignancies, current approaches are limited to overexpression of one or a few transgenes, constraining the diseases that can be treated with this approach and leading to potential conc
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Science current issue
A pathway for mitotic chromosome formationMitotic chromosomes fold as compact arrays of chromatin loops. To identify the pathway of mitotic chromosome formation, we combined imaging and Hi-C analysis of synchronous DT40 cell cultures with polymer simulations. Here we show that in prophase, the interphase organization is rapidly lost in a condensin-dependent manner, and arrays of consecutive 60-kilobase (kb) loops are formed. During prome
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Science current issue
War and peace in the nuclear age
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Science current issue
News at a glance
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Science current issue
Design for U.S. exascale computer takes shape
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Science current issue
China's planned exascale computer threatens Summit's position at the top
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Science current issue
Psychiatrists begin to map genetic architecture of mental disorders
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Science current issue
Use of cholera vaccines expands, raising hopes
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Science current issue
Gene therapy field hit by fresh safety concern
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Science current issue
Tobacco giant's research largesse ignites controversy
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Science current issue
As polar ozone mends, UV shield closer to equator thins
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Science current issue
The happiness project
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Science current issue
China's AI imperative
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Science current issue
An indoor chemical cocktail
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Science current issue
Toward an optically controlled brain
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Science current issue
Cholesterol crystals impede nerve repair
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Science current issue
How hummingbirds stay nimble on the wing
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Science current issue
When quantum optics meets topology
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Science current issue
Revising concepts about adult stem cells
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Science current issue
Superradiators created atom by atom
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Science current issue
Open data sharing and the Global South--Who benefits?
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Science current issue
Data rich
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Science current issue
Better together
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Science current issue
Białowieza Forest: Political stands
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Science current issue
Białowieza Forest: Logging data lacking
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Science current issue
Transport expansion threatens the Arctic
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Science current issue
A window on hippocampal neurogenesis
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Science current issue
Genes overlap across psychiatric disease
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Science current issue
Interactions of LARKS protein domains
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Science current issue
Safer without PUMA
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Science current issue
Building up to superradiance, one by one
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Science current issue
Protecting the heart by destabilizing mRNA
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Science current issue
Crystallography of sensitive materials
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Science current issue
Making quick turns
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Science current issue
Connecting quantum emitters
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Science current issue
Toward programmed therapeutics
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Science current issue
Keeping cholesterol at bay
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Science current issue
Tracking mitotic chromosome formation
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Science current issue
Stimulating deep inside the brain
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Science current issue
Seeding a laser amplifier
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Science current issue
When do you really need SRP?
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Science current issue
Do we know the air we breathe indoors?
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Science current issue
At home in the pancreas
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Science current issue
A brain rhythm for speech integration
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Science current issue
Programmed nanoparticle stacking
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Science current issue
Scalable h-BN sheets
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Migration without a nucleus
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Unfocused eyes in the stars
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Science current issue
COPD risk: Clues from the tree branches
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Big Think
Digital deception: We 'love' using our devices and it's making us miserable"Obviously, technology product and app designers seek to entice us to use their products. Few designers, however, are worried about the adverse effects of encouraging overuse." Read More
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Science | The Guardian
What terminally ill children taught this doctor about how to liveDr Alastair McAlpine asked some of young patients what gave them joy and meaning – their answers surprised him As a pediatric palliative care physician, I spend my days working with children who have life-threatening or life-limiting illnesses and their families. Although many people think of us as the harbingers of death, in reality, doctors like us aim to maximize quality of life, especially wh
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The Atlantic
The Case for a Big, Beautiful Military ParadePresident Trump asked the Pentagon “ to explore a celebration at which all Americans can show their appreciation ” for America’s military, so we might be seeing the first national military parade since 1991 . Will it cost millions? Probably. Will there be counter-demonstrations? Sure. Is there a risk of terrorist attacks? Of course. Should it happen? Absolutely, and here’s why. America’s military
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The Atlantic
Democrats' 'Resistance' to Trump Is Eroding, and So Are Their Poll NumbersRemember “this is not normal?” A year ago, it was the motto of the self-styled “Resistance”—the coalition of liberals, Democrats, and a few wayward conservatives who were implacably opposed to the Trump administration. The endless refrain represented the refusal to countenance Trump as an ordinary political actor. Doing so, they feared, would eventually lead to the acceptance of racism, xenophobi
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Ingeniøren
Borgerforslag: »Vi vil gøre ulovlig logning ulovlig«Nu er der rejst forslag om at annullere logningsbekendtgørelsen, der - mod EUs dom - betyder, at danskere fortsat overvåges af myndighederne.
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Ingeniøren
Forskere holdt vejret: En Falcon Heavy-ulykke ville have forsinket stort dansk rumprojektTerma og DTU Space kan – forhåbentligt – ånde lettet op. Fejl på Falcon Heavy kunne have spændt ben for opsendelsen af danske instrumenter til rumstationen.
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Ingeniøren
Hør ugens podcast om Falcon Heavy og peer reviewIngeniørens ugentlige podcast, Transformator, sætter denne gang fokus på SpaceX’ opsendelse af den Falcon Heavy-raketten og de perspektiver, der tegner sig oven på succesen. Vi kaster også et kritisk blik på peer review-processen til kvalitetskontrol af videnskabelige forskningsartikler.
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Dagens Medicin
Nyt nordisk samarbejde skal forebygge ufrivillig barnløshedOrganisationer i de nordiske lande står bag en ny tænketank, som skal modvirke ufrivillig barnløshed. Det er verdens første tværnationale initiativ på området.
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Ingeniøren
There's a starman in the sky ...but why?En rød sportsvogn svæver nu rundt i kredsløb om Solen efter en af rumfartens største begivenheder siden månerejsen. Men hvad er budskabet?
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Dagens Medicin
Specialet i akutmedicin er en realitetMålbeskrivelsen for det akutmedicinske speciale er færdig, meddeler Sundhedsministeriet. De første uddannelsesforløb forventes at blive opslået med start til efteråret.
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EurekAlert! - Breaking News
UChicago astrophysicists settle cosmic debate on magnetism of planets and starsUsing one of the world's most powerful laser facilities, a team led by University of Chicago scientists experimentally confirmed a long-held theory for cosmic magnetic field generation: the turbulent dynamo. By creating a hot turbulent plasma the size of a penny, that lasts a few billionths of a second, the researchers recorded how the turbulent motions can amplify a weak magnetic field to the str
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EurekAlert! - Breaking News
Special UV light safely kills airborne flu virus, finds studyOverhead far-UVC light, a type of ultraviolet light that is harmless to humans, effectively killed airborne flu virus, found researchers at Columbia University. The lighting may offer a new weapon against the spread of flu virus in public spaces.
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EurekAlert! - Breaking News
Direct link between glands and implanting embryos critical to pregnancyResearchers used 3-D imaging with molecular testing to uncover new insight into the earliest stages of mammalian pregnancy -- offering clues to unsolved questions in pregnancy. Reporting Feb. 9 in Nature Communications, the scientists demonstrate in mice that glands in the uterus must link and communicate directly with the embryo so it will implant and begin pregnancy.
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EurekAlert! - Breaking News
Giant lava dome confirmed in Japan's Kikai CalderaResearchers have confirmed that a giant lava dome was created in the Kikai Caldera, south of Japan's main islands after the caldera-forming supereruption 7,300 years ago. The dome is in the world's largest class of post-caldera volcano, with a volume of over 32 cubic kilometers. It is possible that currently a giant magma buildup may exist under the Kikai Caldera.
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EurekAlert! - Breaking News
Organic food provides significant environmental benefits to plant-rich dietsA study of the diets of 34,000 people confirms that a diet high in fruit and vegetables is better for the planet than one high in animal products. The study also finds that organic food provides significant, additional climate benefits for plant-based diets, but not for diets with only moderate contribution from plant products. This is the first-ever study to look at the environmental impacts of b
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Phys.org - latest science and technology news stories
'Sinking' Pacific nation is getting bigger: studyThe Pacific nation of Tuvalu—long seen as a prime candidate to disappear as climate change forces up sea levels—is actually growing in size, new research shows.
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Science | The Guardian
Dippy the dinosaur unveiled in Dorset on first leg of UK tourDiplodocus skeleton that graced Natural History Museum begins new life on Jurassic Coast For more than a century Dippy the dinosaur amazed and inspired visitors to the Natural History Museum (NHM) in London. On Friday, the diplodocus skeleton cast was unveiled 130 miles away near the Jurassic Coast at the Dorset County Museum in Dorchester on the first stage of an eight-stop tour of the UK. Conti
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Phys.org - latest science and technology news stories
Organic food provides significant environmental benefits to plant-rich dietsA major new study confirms that a diet high in fruit and vegetables is better for the planet than one high in animal products. The study also finds that organic food provides significant, additional climate benefits for plant-based diets, but not for diets with only moderate contribution from plant products. Published today in open access journal Frontiers in Nutrition, this is the first study to
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Phys.org - latest science and technology news stories
Astrophysicists settle cosmic debate on magnetism of planets and starsThe universe is highly magnetic, with everything from stars to planets to galaxies producing their own magnetic fields. Astrophysicists have long puzzled over these surprisingly strong and long-lived fields, with theories and simulations seeking a mechanism that explains their generation.
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The Atlantic
When Divorce Is an OpportunitySTOCKHOLM—Sweden has the reputation of being one of the best countries in the world for gender equality. The women’s employment rate in Sweden is the highest in the European Union, and is nearly equal to the men’s employment rate. Nearly 90 percent of Swedish fathers take paternity leave—it is not unusual to see men pushing baby carriages alone in the city. This can be disconcerting for the hundr
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Ingeniøren
Transportminister bryder loven og ignorerer statsrevisorers kritik i IC4-sagenTransportministeren gør ikke rede for, hvad han vil gøre som konsekvens af Rigsrevisionens afdækning af nye problemer i IC4-sagen. Det er klart ulovligt, siger professor i forvaltningsret. Han bakkes op af statsrevisorerne.
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Phys.org - latest science and technology news stories
Premier League launches rights auction as tech giants waitThe Premier League launches its latest auction of domestic live broadcast rights on Friday but football finance experts say global tech giants such as Amazon and Facebook are not yet ready to enter the fray.
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Phys.org - latest science and technology news stories
Canadian provinces feud over Pacific pipeline projectA pipeline project aimed at boosting Canada's overseas oil sales and reducing reliance on US buyers has pitted two provincial governments against each other, sticking the prime minister in the middle.
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Phys.org - latest science and technology news stories
China's Didi Chuxing takes aim at Japan's taxi marketChinese ride-hailing giant Didi Chuxing announced a deal with Japanese telecom firm SoftBank on Friday to develop a taxi app in Japan, where services like Uber have struggled to make inroads.
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Phys.org - latest science and technology news stories
New raids on Japan crypto exchanges after Coincheck hackJapan said on Friday it had carried out raids on a number of cryptocurrency exchanges following a massive hack that saw thieves steal $530 million in virtual currency.
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Phys.org - latest science and technology news stories
Canada moves to speed environmental reviews of energy projectsCanada unveiled plans Thursday to speed up environmental reviews of mines, pipelines and dam projects, placing the approval process under a single agency.
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Phys.org - latest science and technology news stories
News Corp CEO rails at 'dysfunctional' online environmentNews Corp's chief executive on Thursday took a swipe at Google and Facebook for fostering a "dysfunctional" and "debased" online environment which harms the news media and responsible journalism.
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Phys.org - latest science and technology news stories
China's January auto sales growth rebounds to 10.7 percentChina's auto sales growth rebounded in January into positive territory, boosted by strong demand for SUVs, an industry group reported Friday.
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Phys.org - latest science and technology news stories
The black box set to revolutionize the search for life beyond EarthIn the world's driest desert, an unassuming black box called "Espresso" is about to begin a very big mission: scouring the universe for planets like ours to find signs of life beyond Earth.
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Phys.org - latest science and technology news stories
At least 8,000 great white sharks off Australia coast: researchersAt least 8,000 great white sharks roam the waters off Australia, according to research released Friday that is likely to renew debate about balancing conservation efforts with mitigating attacks.
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Phys.org - latest science and technology news stories
Qualcomm rejects Broadcom hostile bid, opens door to talksQualcomm on Thursday rejected a record $121 billion hostile bid from computer chip rival Broadcom but offered to meet with the Singapore-based firm to discuss the recently increased offer.
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Phys.org - latest science and technology news stories
Green cars in spotlight as India eyes electric revolutionElectric cars bask in the limelight at India's flagship auto show, where an ambitious plan to phase out polluting clunkers has manufacturers racing to lure millions of new drivers to their green vehicles.
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Phys.org - latest science and technology news stories
Top Brazilian paper to stop publishing on FacebookOne of Brazil's top newspapers, the Folha de S. Paulo, announced Thursday it would stop publishing on its Facebook page after the social network announced it would give personal content more visibility.
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Phys.org - latest science and technology news stories
Mass production of new class of semiconductors closer to realityTwo Waterloo chemists have made it easier for manufacturers to produce a new class of faster and cheaper semiconductors.
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Ingeniøren
Ugens it-job: Softwareudvikler hos BEC eller job i Forsvarets EfterretningstjenestePå dagens liste er der job for både teknikere, ledere, arkitekter og udviklere. Find det rette job for dig.
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Phys.org - latest science and technology news stories
Drivers of hate in the U.S. have distinct regional differencesIn a new study, University of Utah geographers sought to understand the factors fueling hate across space. Their findings paint a rather grim reality of America; hate is a national phenomenon, and more complicated than they imagined.
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Phys.org - latest science and technology news stories
Socioecological network finds space for cattle, fish, and people in the big mountain westTension between the needs of cattle and fish is a source decades of controversy in northeast Oregon's Blue Mountains. Endangered bull trout, steelhead trout, Chinook salmon, and sockeye salmon require cold, clear water in mountain streams to thrive and reproduce. Cattle need these same streams for water, heat relief, and valuable streamside browse. But grazing cattle can muddy the water and trampl
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Nyheder - Forskning - Videnskab
Skizofreni, autisme og depression deler genetisk aktivitetMange sygdomme bliver mere eller mindre genetisk båret videre fra generation til generation. Men...
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Phys.org - latest science and technology news stories
Simple rules can help fishery managers cope with ecological complexityTo successfully manage fisheries, factors in the environment that affect fish—like food sources, predators and habitat—should be considered as part of a holistic management plan.
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Phys.org - latest science and technology news stories
Metasurfaces enable improved optical lens performanceProducing the perfect color images we need and love often requires multiple, heavy lenses so that each color focuses in exactly the same plane. Now Penn State engineers have developed a new theory that solves the problem using a single thin lens comprised of gradient index materials and metasurface layers to properly direct the light.
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Phys.org - latest science and technology news stories
AI computer vision breakthrough IDs poachers in less than half a secondThousands of animals including elephants, tigers, rhinos, and gorillas are poached each year. Researchers at the USC Center for Artificial Intelligence in Society have long been applying AI to protect wildlife. Initially, computer scientists were using AI and game theory to anticipate the poachers' haunts, and now they have applied artificial intelligence and deep learning to spot poachers in near
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Phys.org - latest science and technology news stories
NASA seeks the gold in Winter Olympics snowNASA engineer Manuel Vega can see one of the Olympic ski jump towers from the rooftop of the South Korean weather office where he is stationed. Vega is not watching skiers take flight, preparing for the 2018 PyeongChang Winter Olympics and Paralympic games. Instead, he's inspecting the SUV-sized radar beside him. The instrument is one of 11 NASA instruments specially transported to the Olympics to
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Dagens Medicin
Et onemanshow takker afRegionerne har i sine første ti år været synonym med Bent Hansen. Nu siger den gamle socialdemokrat farvel. Her fortæller han bl.a. om sine sejre og nederlag, om rigtige og forkerte socialdemokrater, om ikke at blive sundhedsminister og om personlig chikane.
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Dagens Medicin
Den bedste sundhedsminister, vi ikke har haftBent Hansen forlader en skude, som nok sejler, men som savner retning og kræver en lige så stærk skipper som ham selv.
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Dagens Medicin
Status: Så langt er regionerne med de nye Steno-centreI fire ud af fem regioner er bevillinger og placeringer til de kommende, regionale Steno Diabetes Centre på plads. Når den sidste region er på plads, vil Novo Nordisk Fonden have bevilget over syv mia. kr. til satsningen
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Dagens Medicin
Drejebogen for Steno Diabetes Center Sjælland er i støbeskeenTidligere forskningschef på Nordsjællands Hospital, Lise Tarnow, skal som netop tiltrådt projektchef løfte opgaven med at føre planerne for Region Sjællands Steno Diabetes Center ud i livet. Regionens demografi fordrer et tæt samarbejde med primærsektor, psykiatri og kommuner.
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EurekAlert! - Breaking News
Drivers of hate in the US have distinct regional differencesIn a new study, University of Utah geographers sought to understand the factors fueling hate across space. Their findings paint a rather grim reality of America; hate is a national phenomenon, and more complicated than they imagined. The researchers mapped the patterns of active hate groups in every US county in the year 2014, and analyzed their potential socioeconomic and ideological drivers.
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Dagens Medicin
IT-system forsinker indberetning af data fra praksisGenopretningen af data om diabetespatienter i almen praksis er forsinket flere måneder. En række andre it-projekter er årsag til, at det har taget længere tid end forventet.
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Viden
SPIL Kan du gøre Gitte gravid?Kan du styre sædcellen forbi forhindringerne mod ægget og gøre Gitte Liv gravid?
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Ingeniøren
Stort spring i beregningskraft med nyt AI-center på Københavns UniversitetEt nyt center på Københavns Universitet skal analysere data på tværs af videnskabsområder, som indtil nu har været for store eller komplekse at angribe.
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Ingeniøren
Elendig it-sikkerhed hos praktiserende læger: I fare for hackingEn ny rapport fra it-sikkerhedsselskabet Ezenta påpeger graverende fejl i it-sikkerheden hos praktiserende læger.
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Science | The Guardian
‘I could hear things, and I could feel terrible pain’: when anaesthesia failsAnaesthesia remains a mysterious and inexact science – and thousands of patients still wake up on the operating table every year. By Kate Cole-Adams When Rachel Benmayor was admitted to hospital, eight and a half months pregnant, in 1990, her blood pressure had been alarmingly high and her doctor had told her to stay in bed and get as much rest as possible before the baby came. But her blood pres
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Ingeniøren
Leder: Eltog med kun 200 km/t er en halvhjertet satsning
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Viden
TEGNESERIE Sådan fører klamydia krig i dine kønsdeleBakterier trænger ind i dine slimhinder og begynder at kopiere sig selv. Se hvad det sker i kroppen, når du får klamydia.
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Science | The Guardian
Asteroid passing close to Earth today – no need to worryThe space rock 2018 CB is up to 40m long and will come within 64,000km of the planet’s surface An asteroid is headed our way – the second this week – but there’s no need to worry. The newly discovered space rock will pass within 39,000 miles (63,000km) of Earth on Friday evening GMT. That’s less than one-fifth the distance to the moon. Continue reading...
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EurekAlert! - Breaking News
Mass production of new class of semiconductors closer to realityTwo Waterloo chemists have made it easier for manufacturers to produce a new class of faster and cheaper semiconductors.
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EurekAlert! - Breaking News
Ultra-efficient removal of carbon monoxide using gold nanoparticles on a molecular supportResearchers from Tokyo Metropolitan University have developed a way to mount gold nanoparticles on a molecular support known as a polyoxometalate (POM). They successfully applied this to realize nearly 100% conversion of carbon monoxide (CO) over a wide temperature range, demonstrating stable performance over long periods of time. They showed how traces of water uniquely contribute to the catalyst
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EurekAlert! - Breaking News
Workplace stress can take a toll on your brain surgeon, tooA new study by the Keck School of Medicine of USC finds that two-thirds of neurosurgeons experience burnout during training, and stressors at work are partly to blame.
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EurekAlert! - Breaking News
New findings about why losartan is effective in treating Marfan syndrome may reshape our thinking about patient managementProgressive dilation of the aortic root is considered one of the most serious manifestations of Marfan syndrome. The antihypertensive losartan is one of the two medications recommended by current guidelines attenuate the progression of this aortic enlargement, but which medication works best is still controversial. A new report in The American Journal of Pathology confirms losartan's efficacy but
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BBC News - Science & Environment
Dippy the diplodocus starts UK tour in DorchesterThe 70ft-long (21m) dinosaur replica only just squeezed into its new home in Dorset.
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The Atlantic
Radio Atlantic: From 'I, Tonya' to 'Cat Person,' Is 'Based On a True Story' Better?Conor Friedersdorf recently argued in The Atlantic that in this moment, when the truth is bitterly contested, fiction presents us an opportunity. It allows us to step into another person’s perspective and talk about gray areas without the problems of detailing an actual person’s private moments. But does blurring the lines between truth and fiction undermine the messy complexities of the real wor
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New on MIT Technology Review
Social networks are broken. This man wants to fix them.Ethan Zuckerman on fighting social media’s echo chamber.
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Science | The Guardian
Space exploration should be an initiative of nations, not just some rich guy | Van BadhamThere are times I really hope that intelligent life from outer space is NOT observing us Maybe it’s because Robert Lepage is touring The Far Side of the Moon to the Adelaide Festival. Or that a new Star Trek is on TV. Or maybe it’s because I feel like the only person alive who really – really – liked Luc Besson’s Valerian, but space, fantasies of the final frontier, and the real voyages that huma
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Ingeniøren
Tre dårlige chefvaner, som forpester hverdagenNogle fejl plager mange ledere, og det fører til ringere præstationer og dårligere holdfølelse. Derfor er det vigtigt at kunne løse tre typiske udfordringer, som mange møder i arbejdet med deres chef.
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Ingeniøren
Det kniber med kvaliteten af forskningens kvalitetstjekGummistempel eller kvalitetsstempel? Et af fundamenterne for den videnskabelige proces, peer reviews, fungerer ikke som tænkt og ønsket. Men findes der et bedre system? Spørgsmålet deler forskerne.
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Live Science
What Are Microwaves?Microwaves are a type of electromagnetic radiation, and are useful in communications, radar and cooking.
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Latest Science News -- ScienceDaily
Termites' unique gut 'factory' key to global dominationTermites have achieved ecological dominance and now some ingredients for their success have been determined to lie in their unique gut microbiome 'factories' -- which enable the creatures to eat wood and other material relatively free of competition. New research shows the majority of termite gut microorganisms is not found in any other animals and that they are not only inherited from parents but
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Latest Science News -- ScienceDaily
Quantum dots display promise for polymersScientists are employing the power of the sun to build functional synthetic polymers using photosensitive, semiconducting quantum dots as a catalyst.
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Latest Science News -- ScienceDaily
Nature, meet nurtureIs it nature or nurture that ultimately shapes an organism? A new study reveals a dramatic landscape of gene expression changes across all cell types in the mouse visual cortex after a sensory experience, many linked to neural connectivity and the brain's ability to rewire itself to learn and adapt.
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Latest Science News -- ScienceDaily
'Smart thermometer' improves flu forecastingA new approach shows that de-identified data from a 'smart thermometer' connected to a mobile phone app can track flu activity in real time at both population and individual levels and the data can be used to significantly improve flu forecasting.
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Latest Science News -- ScienceDaily
Biologists decipher a key piece of the odor-detection puzzle in flies, mosquitoesBiologists have discovered surprisingly that the complex odor-detecting machinery of the fruit fly Drosophila is heavily influenced by one specific odor receptor. This same receptor also exists in crop-damaging fly species and disease-carrying mosquitoes, opening the possibility for new chemical cocktails to control pests and render people
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Latest Science News -- ScienceDaily
Molecular mechanisms of memory formation revelaedNeuroscientists have uncovered a cellular pathway that allows specific synapses to become stronger during memory formation. The findings provide the first glimpse of the molecular mechanism by which long term memories are encoded in a region of the hippocampus called CA3.
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Latest Science News -- ScienceDaily
Breakthrough technique combats cancer drug resistanceThe ability for cancer cells to develop resistance to chemotherapy drugs -- known as multi-drug resistance -- remains a leading cause for tumor recurrence and cancer metastasis, but recent findings offer hope that oncologists could one day direct cancer cells to 'turn off' their resistance capabilities.
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NeuWrite San Diego
Did you do that?Limited only perhaps by my emotional fortitude and physical abilities, I am unquestionably in control of myself. This sense is perhaps drawn most into question first thing in the morning when I play both sides of an internal civil war: on one side, my bed, on the other, the cold cruel world. Both sides battle […]
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Latest Science News -- ScienceDaily
Rocky or gassy? Massive, dense super-Earth planet detectedA star about 100 light years away in the Pisces constellation, GJ 9827, hosts what may be one of the most massive and dense super-Earth planets detected to date, according to new research. This new information provides evidence to help astronomers better understand the process by which such planets form.
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Latest Science News -- ScienceDaily
Gut bacteria can be good, and bad, for healthA new study found that impairing a rare group of cells (called Paneth cells) in the small intestine allows gut bacteria to invade the organ and cause major inflammation. The study was conducted in mice, but has implications for the treatment of inflammatory bowel disease (IBD), a group of disorders characterized by chronic inflammation in the digestive track.
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The Atlantic
The U.S. Government Shut Down—and Reopened—While You Were SleepingUpdated on February 9 at 8:40 a.m. ET There was no reason for Senate Majority Leader Mitch McConnell to feel nervous on Thursday morning. The day before, he and Senate Minority Leader Chuck Schumer had announced an agreement on a massive two-year budget deal to attach to a short-term funding bill. A few Senate Republicans were annoyed, to be sure—the deal busts through budget caps, allocating nea
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New Scientist - News
Primitive human eggs matured in the lab for the first timeHuman eggs have been removed in their most primitive state and brought to maturity in the lab for the first time, potentially boosting fertility treatments.
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Latest Science News -- ScienceDaily
Researchers run first tests of unique system for welding highly irradiated metal alloysScientists are conducting tests of a new system that will allow researchers to advance welding technologies for repair of irradiated materials by developing processing conditions and evaluating post-weld materials properties.
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Latest Science News -- ScienceDaily
Molecular 'magnets' could improve cancer immunotherapyChemicals that attract specialized immune cells toward tumors could be used to develop better immunotherapies for cancer patients, according to new research. Scientists have discovered that immune cells called Natural Killer cells accumulate in tumors and release chemicals that attract specialized dendritic cells (cDC1) -- white blood cells known for triggering anti-cancer immune responses -- to t
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Latest Science News -- ScienceDaily
When it comes to genes, lichens embrace sharing economyResearchers have discovered the first known molecular evidence of obligate symbiosis in lichens, a distinctive co-evolutionary relationship that could shed new light on how and why some multicellular organisms consolidate their genomes in order to co-exist.
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Popular Science
Chinese cops are using facial-recognition sunglasses. Here’s how that tech works.Technology There's at least one big problem in the field. Facial-recognition technology is no longer a gimmick seen in dystopian science fiction movies. This is how it works.
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Ingeniøren
Bagsiden: BREAKING: Danske Spil bruger ikke matematikUgens gevinstchancer
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Ingeniøren
Bagsiden: Ugens lokalhistorie
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Ingeniøren
Bagsiden: Seruminstituttet revisitedUgens historiske skandale

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